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BMPR1A/ALK-3 Protein, Human, Recombinant (hFc & His)
(Synonyms: SKR5, Serine/Threonine-Protein Kinase Receptor R5, CD292, Bone Morphogenetic Protein Receptor Type-1A, BMPR-1A, BMPR1A, BMP Type-1A Receptor, ALK-3, ALK3, ACVRLK3, Activin Receptor-Like Kinase 3) Copy Product InfoSynonyms: SKR5, Serine/Threonine-Protein Kinase Receptor R5, CD292, Bone Morphogenetic Protein Receptor Type-1A, BMPR-1A, BMPR1A, BMP Type-1A Receptor, ALK-3, ALK3, ACVRLK3, Activin Receptor-Like Kinase 3
Catalog No. TMPJ-00325 Copy Product Info
Bone Morphogenetic Protein Receptor Type-1A (BMPR1A) belongs to the TKL Ser/Thr protein kinase family and TGFB receptor subfamily, including the type I receptors BMPR1A and BMPR1B and the type II receptor BMPR2. BMPR1A is a single-pass type I membrane protein and highly expressed in skeletal muscle. BMPR1A contains one GS domain and one protein protein kinase domain. BMPR1A is necessary for the extracellular matrix depostition by osteoblasts. BMPR1A can activate SMAD transcriptional regulators, binding with ligands. Defects in BMPR1A are a cause of juvenile polyposis syndrome, Cowden disease and hereditary mixed polyposis syndrome 2 (HMPS2).
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 5 μg | $39 | 7-10 days | 7-10 days | |
| 10 μg | $60 | 7-10 days | 7-10 days | |
| 20 μg | $96 | 7-10 days | 7-10 days | |
| 50 μg | $183 | 7-10 days | 7-10 days | |
| 100 μg | $335 | 7-10 days | 7-10 days | |
| 200 μg | $615 | 7-10 days | 7-10 days | |
| 500 μg | $1,390 | 7-10 days | 7-10 days | |
| 1 mg | $1,980 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Bioactivity | Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first. |
| Description | Bone Morphogenetic Protein Receptor Type-1A (BMPR1A) belongs to the TKL Ser/Thr protein kinase family and TGFB receptor subfamily, including the type I receptors BMPR1A and BMPR1B and the type II receptor BMPR2. BMPR1A is a single-pass type I membrane protein and highly expressed in skeletal muscle. BMPR1A contains one GS domain and one protein protein kinase domain. BMPR1A is necessary for the extracellular matrix depostition by osteoblasts. BMPR1A can activate SMAD transcriptional regulators, binding with ligands. Defects in BMPR1A are a cause of juvenile polyposis syndrome, Cowden disease and hereditary mixed polyposis syndrome 2 (HMPS2). |
| Species | Human |
| Expression System | HEK293 Cells |
| Tag | C-hFc-6xHis |
| Accession Number | P36894 |
| Amino Acid | Gln24-Arg152 |
| Construction | Gln24-Arg152 |
| Protein Purity | Greater than 95% as determined by reducing SDS-PAGE. (QC verified) |
| Endotoxin | < 0.1 ng/µg (1 EU/µg) as determined by LAL test. |
| Formulation | Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. |
| Reconstitution | Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing. |
| Stability & Storage | Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
| Shipping | In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice. |
| Synonyms | SKR5, Serine/Threonine-Protein Kinase Receptor R5, CD292, Bone Morphogenetic Protein Receptor Type-1A, BMPR-1A, BMPR1A, BMP Type-1A Receptor, ALK-3, ALK3, ACVRLK3, Activin Receptor-Like Kinase 3 |
| Research Background |
| Molecular Weight | 60 KDa (reducing condition) |
| Storage | Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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Related Tags: BMPR1A/ALK-3 Protein, Human, Recombinant (hFc & His) chemical structure | BMPR1A/ALK-3 Protein, Human, Recombinant (hFc & His) molecular weight
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