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Anti-VISTA Antibody-PE (5Q796) is a PE-conjugated Mouse antibody targeting VISTA. Anti-VISTA Antibody-PE (5Q796) can be used in FCM.
Description | Anti-VISTA Antibody-PE (5Q796) is a PE-conjugated Mouse antibody targeting VISTA. Anti-VISTA Antibody-PE (5Q796) can be used in FCM. |
Ig Type | Monoclonal Mouse IgG1 |
Clone | 5Q796 |
Reactivity | Human |
Verified Activity | Flow cytometric analysis of Human B7-H5(C10orf54) expression on human whole blood Granulocytes. Cells were stained with PE-conjugated anti-Human B7-H5(C10orf54). The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of viable Granulocytes. |
Application | FCM |
Recommended Dose | 10 μl/Test, 0.1 mg/ml |
Antibody Type | Monoclonal |
Host Species | Mouse |
Construction | This product is a recombinant monoclonal antibody expressed from HEK293 cells and conjugated with PE under optimum conditions, the unreacted PE was removed. |
Purification | Protein A |
Appearance | Liquid |
Formulation | PBS solution containing 0.5% BSA and 0.03%ProClin300 |
Research Background | VSIR (V-Set Immunoregulatory Receptor, also known as VISTA) is a Protein Coding gene. VISTA is an immunoregulatory receptor that inhibits the T-cell response. It may promote differentiation of embryonic stem cells, by inhibiting BMP4 signaling. VSIR, or V-set immunoregulatory receptor, could be involved in the pathogenesis of chronic rhinosinusitis with nasal polyps. V-domain Immunoglobulin Suppressor of T cell Activation (VISTA) is an inhibitory immune-checkpoint molecule that suppresses CD4+ and CD8+ T cell activation when expressed on antigen-presenting cells. VSIR is broadly expressed in the spleen, bone marrow, and other tissues. Diseases associated with VSIR include Ichthyosis, Congenital, Autosomal Recessive 6, and Monckeberg Arteriosclerosis. An important paralog of this gene is VSIG8. |
Conjucates | PE |
Others Formats | Unconjugated/FITC |
Antibody Types Available | 3 |
Immunogen | Recombinant Human VISTA Protein (TMPY-03219) |
Antigen Species | Human |
Stability & Storage | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. |
Transport | Shipping with blue ice. |
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