CCL4 Protein, Rat, Recombinant (His)

Name: CCL4 Protein, Rat, Recombinant (His)
Brand: TargetMol
SKU: TMPY-04695
Price: 77 USD
Availability: InStock
Rating: 5 (10 reviews)

(Synonyms: chemokine (C-C motif) ligand 4) Copy Product Info

Synonyms: chemokine (C-C motif) ligand 4

Catalog No. TMPY-04695 Copy Product Info

CCL4 Protein, Rat, Recombinant (His) is expressed in yeast with His tag. The predicted molecular weight is 9.2 kDa and the accession number is P50230.

Pack Size	Price	USA Stock	Global Stock
5 µg	$77	-	In Stock
10 µg	$123	-	In Stock
20 µg	$198	-	In Stock
50 µg	$397	7-10 days	7-10 days
100 µg	$790	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Batch Information

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Purity:> 90 % as determined by SDS-PAGE

Appearance:Lyophilized powder

Color:White

Resource Download

COA User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	Activity testing is in progress. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Description	CCL4 Protein, Rat, Recombinant (His) is expressed in yeast with His tag. The predicted molecular weight is 9.2 kDa and the accession number is P50230.
Species	Rat
Expression System	P. pastoris (Yeast)
Tag	C-His
Accession Number	P50230
Construction	A DNA sequence encoding the rat Ccl4 (NP_446310.1) (Ala24-Asn92) was expressed with a polyhistidine tag at the C-terminus. Predicted N terminal: Ala 24
Protein Purity	> 90 % as determined by SDS-PAGE.
Endotoxin	Please contact us for more information.
Formulation	Lyophilized from a solution filtered through a 0.22 μm filter, containing 30% CAN, 0.1% TFA. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
Reconstitution	Reconstituted with sterile deionized water to 0.25 mg/mL. Reconstitution conditions may vary depending on the lot.
Synonyms	chemokine (C-C motif) ligand 4
Research Background	CCL4 (C-C chemokine ligand 4), is a macrophage inflammatory protein with a chief effect in inflammation and immune-regulation, and was documented in cancer progression by promoting instability in the tumor environment. The inflammatory chemokine (C-C motif) ligand 4 (CCL4) plays an important role in the pathogenesis and progression of cancer. In particular, higher serum CCL4 levels in patients with oral squamous cell carcinoma (OSCC) are associated with a more advanced stage of disease. CCL4 may be a new molecular therapeutic target for inhibition of lymphangiogenesis and metastasis in OSCC. CCL3 and CCL4 loci may be marker SNPs for risk of HCV treatment outcome. CCL4 can enhance the recruitment of preosteoclasts to bone in the early stage, and the reduction of CCR5 promotes osteoclastogenesis when RANKL is prevalent.

Chemical Properties

Molecular Weight

9.2 kDa (predicted)

Storage & Solubility Information

Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Storage	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.