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c-Kit/CD117 Protein, Cynomolgus/Rhesus macaque, Recombinant (His)

(Synonyms: SCFR, PBT, KIT, c-kit, ckit, CD117) Copy Product Info

Synonyms: SCFR, PBT, KIT, c-kit, ckit, CD117

Catalog No. TMPK-01270 Copy Product Info
The c-kit proto-oncogen (CD117) has been shown to be present in several cell types including normal and neoplastic hemopoietic cells. Among normal BM cells, CD117 expression has been found in about half of the CD34 precursors including progenitors committed to the erythroid, granulo-monocytic, and megakaryocytic cell lineages.
Pack SizePriceUSA StockGlobal StockQuantity
5 µg$587-10 days7-10 days
10 µg$927-10 days7-10 days
20 µg$1487-10 days7-10 days
50 µg$2897-10 days7-10 days
100 µg$4877-10 days7-10 days
200 µg$8837-10 days7-10 days
500 µg$1,9507-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Bioactivity
Immobilized Human SCF, No Tag at 5μg/ml (100μl/Well) on the plate. Dose response curve for Cynomolgus/Rhesus macaque CD117, His Tag with the EC50 of 4.76μg/ml determined by ELISA.
Description
The c-kit proto-oncogen (CD117) has been shown to be present in several cell types including normal and neoplastic hemopoietic cells. Among normal BM cells, CD117 expression has been found in about half of the CD34 precursors including progenitors committed to the erythroid, granulo-monocytic, and megakaryocytic cell lineages.
Species
Cynomolgus,Rhesus
Expression System
HEK293 Cells
TagC-His
Accession NumberXP_005555332.1
ConstructionGln26-Pro520
Protein Purity
> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
Endotoxin< 1.0 EU/μg of the protein as determined by the LAL method.
FormulationLyophilized from a solution filtered through a 0.22 μm filter, containing PBS (pH 7.4). Typically, 8% trehalose is incorporated as a protective agent before lyophilization.
ReconstitutionReconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
SynonymsSCFR, PBT, KIT, c-kit, ckit, CD117
Research Background
The c-kit proto-oncogen (CD117) has been shown to be present in several cell types including normal and neoplastic hemopoietic cells. Among normal BM cells, CD117 expression has been found in about half of the CD34 precursors including progenitors committed to the erythroid, granulo-monocytic, and megakaryocytic cell lineages.
Chemical Properties
Molecular Weight56.69 kDa (predicted). Due to glycosylation, the protein migrates to 90-110 kDa based on Tris-Bis PAGE result.
Storage & Solubility Information
ShippingIn general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
StorageIt is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

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Keywords

Related Tags: c-Kit/CD117 Protein, Cynomolgus/Rhesus macaque, Recombinant (His) chemical structure | c-Kit/CD117 Protein, Cynomolgus/Rhesus macaque, Recombinant (His) molecular weight