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Anti-p60 CAF1 Antibody (4X99)

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Catalog No. TMAC-03007

Anti-p60 CAF1 Antibody (4X99) is a Rabbit antibody targeting p60 CAF1. Anti-p60 CAF1 Antibody (4X99) can be used in WB,ICC,IF,IP,IHC,FCM.

Anti-p60 CAF1 Antibody (4X99)

Anti-p60 CAF1 Antibody (4X99)

😃Good
Catalog No. TMAC-03007
Anti-p60 CAF1 Antibody (4X99) is a Rabbit antibody targeting p60 CAF1. Anti-p60 CAF1 Antibody (4X99) can be used in WB,ICC,IF,IP,IHC,FCM.
Pack SizePriceAvailabilityQuantity
50 μL$2967-10 days
100 μL$4977-10 days
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Product Introduction

Bioactivity
Description
Anti-p60 CAF1 Antibody (4X99) is a Rabbit antibody targeting p60 CAF1. Anti-p60 CAF1 Antibody (4X99) can be used in WB,ICC,IF,IP,IHC,FCM.
Ig Type
IgG
Reactivity
Human
Application
Recommended Dose
WB: 1:500-2000; IHC: 1:50-200; ICC:IF: 1:50-200; IP: 1:10-50; FCM: 1:50-100
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionRecombinant Antibody
PurificationProA affinity purified
AppearanceLiquid
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Research BackgroundChromatin assembly factor-1 (CAF-1) is a multisubunit protein complex that comprises three polypeptide subunits known as p150, p60, and p48. CAF-1 is a nucleosome assembly factor that deposits newly synthesized and acetylated histones H3/H4 into nascent chromatin during DNA replication. The p150 subunit of CAF-1 also supports the maintenance of heterochromatin, which requires the synthesis of both new histones and heterochromatin proteins and their orderly assembly during DNA replication. Heterochromatin is characterized as densely coiled chromatin that generally replicates late during S phase, has a low gene density, and contains large blocks of repetitive DNA that is relatively inaccessible to DNA-modifying reagents. In late S phase, p150 directly associates with heterochromatin associated proteins 1 (HP1α, HP1β and HP1γ). As cells prepare for mitosis, CAF-1 p150 and some HP1 progressively dissociate from heterochromatin, coinciding with the phosphorylation of histone H3. The HP1 proteins reassociate with chromatin at the end of mitosis, as histone H3 is dephosphorylated.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein: the C-terminus of Human p60 CAF1
Antigen Species
human
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 61 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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