NY-ESO-1 or New York esophageal squamous cell carcinoma 1 is a well-known cancer-testis antigen (CTAs) with re-expression in numerous cancer types. Its ability to elicit spontaneous humoral and cellular immune responses, together with its restricted expression pattern, have rendered it a good candidate target for cancer immunotherapy.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
100 μg | Inquiry | $ 734.00 | |
1 mg | Inquiry | $ 4,899.00 |
Description | NY-ESO-1 or New York esophageal squamous cell carcinoma 1 is a well-known cancer-testis antigen (CTAs) with re-expression in numerous cancer types. Its ability to elicit spontaneous humoral and cellular immune responses, together with its restricted expression pattern, have rendered it a good candidate target for cancer immunotherapy. |
Species | Human |
Expression System | HEK293 |
Tag | C-His-Avi |
Accession Number | A0A140T913(HLA-A*02:01)&P61769(B2M)&SLLMWITQC |
Synonyms | MY-ESO-1, MHC, ESO1CTAG, NY-ESO-1, CTAG1, LAGE2A, LAGE-2, CT6.1, CTAG1B |
Construction | Recombinant PE-Labeled Human HLA-A*02:01&B2M&NY-ESO-1 (SLLMWITQC) Tetramer Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus. PE-Labeled Human HLA-A*02:01&B2M&NY-ESO-1 (SLLMWITQC) Tetramer is assembled by biotinylated monomer and PE-labeled streptavidin. It contains Gly25-Thr305(HLA-A*02:01), Ile21-Met119(B2M) and SLLMWITQC peptide.[Accession |A0A140T913(HLA-A*02:01)&P61769(B2M)&SLLMWITQC] |
Endotoxin | Less than 1EU per μg by the LAL method. |
Formulation | Supplied as 0.22μm filtered solution in PBS, 100mM L-Arginine, 0.2% BSA (pH 7.4). |
Stability & Storage |
Valid for 6 months from date of receipt when stored at -80°C.Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
Shipping |
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise. |
Research Background | NY-ESO-1 or New York esophageal squamous cell carcinoma 1 is a well-known cancer-testis antigen (CTAs) with re-expression in numerous cancer types. Its ability to elicit spontaneous humoral and cellular immune responses, together with its restricted expression pattern, have rendered it a good candidate target for cancer immunotherapy. |
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Please read the User Guide of Recombinant Proteins for more specific information.
HLA-A*02:01&B2M&NY-ESO-1 (SLLMWITQC) Tetramer Protein, Human, MHC (His & Avi), PE-Labeled MY-ESO-1 MHC ESO1CTAG NY-ESO-1 CTAG1 LAGE2A LAGE-2 CT6.1 CTAG1B recombinant recombinant-proteins proteins protein