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Anti-LAMP3/CD208 Antibody (2U128) (Synonyms: lysosomal associated membrane protein 3, LAMP3)

Catalog No. TMAY-00948 Copy Product Info
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Anti-LAMP3/CD208 Antibody (2U128) is a Rabbit antibody targeting LAMP3/CD208. Anti-LAMP3/CD208 Antibody (2U128) can be used in ELISA(Cap).

Anti-LAMP3/CD208 Antibody (2U128)

Copy Product Info
🥰Excellent
Catalog No. TMAY-00948
Synonyms lysosomal associated membrane protein 3, LAMP3

Anti-LAMP3/CD208 Antibody (2U128) is a Rabbit antibody targeting LAMP3/CD208. Anti-LAMP3/CD208 Antibody (2U128) can be used in ELISA(Cap).

Anti-LAMP3/CD208 Antibody
(2U128)
Pack SizePriceUSA StockGlobal StockQuantity
20 μL$927-10 days7-10 days
100 μL$2697-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-LAMP3/CD208 Antibody (2U128) is a Rabbit antibody targeting LAMP3/CD208. Anti-LAMP3/CD208 Antibody (2U128) can be used in ELISA(Cap).
Synonymslysosomal associated membrane protein 3, LAMP3
Ig Type
Rabbit IgG
Clone
2U128
Reactivity
Human
Specificity
Human LAMP3/CD208
Application
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionThis antibody was obtained from a rabbit immunized with purified, recombinant Human CD208 / DC-LAMP (rh CD208 / DC-LAMP; TMPY-01013; NP_055213.2; Lys28-Thr381).
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundDendritic cell-lysosomal associated membrane protein (DC-LAMP)/CD208, also known as LAMP3, is a member of the lysosomal associated membrane protein (LAMP) family, which is specifically expressed by human dendritic cells (DCs) upon activation and therefore serves as a marker of human DC maturation. Confocal and immunoelectron microscopy showed that mouse DC-LAMP protein co-localizes with lbm180, a specific marker for the limiting membrane of lamellar bodies that contain surfactant protein B. The present study demonstrates that DC-LAMP is constitutively expressed by mouse, sheep, and human type II pneumocytes. DC-LAMP is constitutively expressed in normal type II pneumocytes. DC-LAMP is detected first in the activated human DC within MHC class II molecules-containing compartments just before the translocation of MHC class II-peptide complexes to the cell surface, suggesting a possible involvement in this process. Furthermore, overexpression of LAMP3 is actively involved in tumor invasion through increased migration into lymph-vascular spaces.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein: Human CD208 / DC-LAMP Protein (TMPY-01013)
Antigen Species
Human
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

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