Ald-C2-PEG4-azide

Name: Ald-C2-PEG4-azide
Brand: TargetMol
SKU: T14155
Rating: 4.5 (1 reviews)

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Catalog No. T14155Cas No. 2030118-14-8

Alias N3-PEG4-CH2CH2CHO

Ald-C2-PEG4-azide is a PEG-based linker for PROTACs that joins two essential ligands, enabling selective protein degradation through the ubiquitin-proteasome system within cells.

Ald-C2-PEG4-azide

😃Good

Catalog No. T14155Alias N3-PEG4-CH2CH2CHOCas No. 2030118-14-8

Ald-C2-PEG4-azide is a PEG-based linker for PROTACs that joins two essential ligands, enabling selective protein degradation through the ubiquitin-proteasome system within cells.

Pack Size	Price	USA Warehouse	Global Warehouse
5 mg	$970	4-6 weeks	4-6 weeks
25 mg	$1,758	4-6 weeks	4-6 weeks
50 mg	$2,638	4-6 weeks	4-6 weeks
100 mg	$3,958	4-6 weeks	4-6 weeks

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

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Product Introduction

Bioactivity

Description	Ald-C2-PEG4-azide is a PEG-based linker for PROTACs that joins two essential ligands, enabling selective protein degradation through the ubiquitin-proteasome system within cells.
In vitro	PROTACs consist of two distinct ligands joined by a linker: one ligand targets an E3 ubiquitin ligase, and the other binds to the target protein. They utilize the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
Synonyms	N3-PEG4-CH2CH2CHO

Chemical Properties

Molecular Weight	275.3
Formula	C₁₁H₂₁N₃O₅
Cas No.	2030118-14-8
Relative Density.	no data available

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc