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SLAMF7 Protein, Human, Recombinant (His & Avi), Biotinylated
(Synonyms: SLAMF7, SLAM Family Member 7, Protein 19A, Novel Ly9, Membrane Protein FOAP-12, CS1, CRACC, CD319, CD2-Like Receptor-Activating Cytotoxic Cells, CD2 Subset 1) Copy Product InfoSynonyms: SLAMF7, SLAM Family Member 7, Protein 19A, Novel Ly9, Membrane Protein FOAP-12, CS1, CRACC, CD319, CD2-Like Receptor-Activating Cytotoxic Cells, CD2 Subset 1
Catalog No. TMPJ-00221 Copy Product Info
SLAMF7 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-6xHis-Avi tag. The predicted molecular weight is 35-55 KDa and the accession number is Q9NQ25.
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 5 µg | $129 | 7-10 days | 7-10 days | |
| 10 µg | $213 | 7-10 days | 7-10 days | |
| 20 µg | $355 | 7-10 days | 7-10 days | |
| 50 µg | $625 | 7-10 days | 7-10 days | |
| 100 µg | $963 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Bioactivity | Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first. |
| Description | SLAMF7 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-6xHis-Avi tag. The predicted molecular weight is 35-55 KDa and the accession number is Q9NQ25. |
| Species | Human |
| Expression System | HEK293 Cells |
| Tag | C-6xHis-Avi |
| Accession Number | Q9NQ25 |
| Amino Acid | Ser23-Met226 |
| Construction | Ser23-Met226 |
| Protein Purity | Greater than 95% as determined by reducing SDS-PAGE. (QC verified) |
| Endotoxin | < 0.1 ng/µg (1 EU/µg) as determined by LAL test. |
| Formulation | Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. |
| Reconstitution | Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing. |
| Synonyms | SLAMF7, SLAM Family Member 7, Protein 19A, Novel Ly9, Membrane Protein FOAP-12, CS1, CRACC, CD319, CD2-Like Receptor-Activating Cytotoxic Cells, CD2 Subset 1 |
| Research Background | SLAMF7 is a single-pass type I membrane protein and contains 1 Ig-like C2-type (immunoglobulin-like) domain. SLAMF7 is expressed in NK cells, activated B-cells, NK-cell line but not in promyelocytic, B-cell lines, or T-cell lines. Although the cytoplasmic domain of CS1 contains immunoreceptor tyrosine-based switch motifs (ITSM), which enables to recruite signaling lymphocyte activation molecule (SLAM)-associated protein (SAP/SH2D1A), it activates NK cells in the absence of a functional SAP. SLAMF7 positively regulated natural killer cell functions by a mechanism dependent on the adaptor EAT-2 but not the related adaptor SAP. However, in the absence of EAT-2, CRACC potently inhibited natural killer cell function. It was also inhibitory in T cells, which are typically devoid of EAT-2. Thus, SLAMF7 can exert activating or inhibitory influences on cells of the immune system depending on cellular context and the availability of effector proteins. |
| Molecular Weight | 35-55 KDa (reducing condition) |
| Shipping | In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice. |
| Storage | Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
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Related Tags: SLAMF7 Protein, Human, Recombinant (His & Avi), Biotinylated chemical structure | SLAMF7 Protein, Human, Recombinant (His & Avi), Biotinylated molecular weight
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