Powder: -20°C for 3 years | In solvent: -80°C for 1 year
PRMT5 IN-1 hydrochloride (compound 9) is a hemiacetalamine, a potent inhibitor of the selective protein arginine methyltransferase 5 (PRMT5) with an inhibitory effect on PRMT5/MEP50 (IC50: 11 nM). PRMT5 IN-1 hydrochloride can be converted to an aldehyde under physiological conditions and reacts with C449 to form a covalent adduct.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
25 mg | 10-14 weeks | $ 1,500.00 |
Description | PRMT5 IN-1 hydrochloride (compound 9) is a hemiacetalamine, a potent inhibitor of the selective protein arginine methyltransferase 5 (PRMT5) with an inhibitory effect on PRMT5/MEP50 (IC50: 11 nM). PRMT5 IN-1 hydrochloride can be converted to an aldehyde under physiological conditions and reacts with C449 to form a covalent adduct. |
Molecular Weight | 455.29 |
Formula | C19H20Cl2N4O5 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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PRMT5-IN-1 hydrochloride inhibitor inhibit