Shopping Cart
Remove All
Your shopping cart is currently empty
8-Cyclopentyl-1,3-dimethylxanthine
Copy Product Info
🥰Excellent
Catalog No. T27076Cas No. 35873-49-5
Alias CPT
8-Cyclopentyl-1,3-dimethylxanthine (CPT) is a potent antagonist of adenosine A1 receptor.
8-Cyclopentyl-1,3-dimethylxanthine
Copy Product Info🥰Excellent
Purity: 99.9%
Catalog No. T27076Alias CPTCas No. 35873-49-5
8-Cyclopentyl-1,3-dimethylxanthine (CPT) is a potent antagonist of adenosine A1 receptor.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 10 mg | $34 | In Stock | In Stock | |
| 25 mg | $56 | In Stock | In Stock | |
| 1 mL x 10 mM (in DMSO) | $29 | In Stock | In Stock |
Add to Cart
Add to Quotation
In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Batch Information
Select Batch
Purity:99.9%
Appearance:Solid
Color:White
Contact us for more batch information
Product Introduction
8-Cyclopentyl-1,3-dimethylxanthine AI Summary
8-Cyclopentyl-1,3-dimethylxanthine demonstrates a broad spectrum of bioactivities with significant pharmacological potential. It shows high affinity for adenosine A1 receptors, exhibiting a Ki value as low as 0.46 nM, and effectively binds to adenosine A2 receptors with a Ki value of 3.9 nM. Additionally, it inhibits adenylate cyclase in rat adipocytes with an IC50 of 0.47 nM, indicating strong modulation of adenosine receptor signaling pathways. The compound also displays diuretic activity by increasing urinary volume and altering the excretion of potassium and sodium ions in rats. Moreover, it influences serum creatinine and urea nitrogen concentrations, which suggests potential renal bioactivity. 8-Cyclopentyl-1,3-dimethylxanthine has moderate affinity for adenosine A3 receptors (Ki=1300.0 nM) and exhibits a diverse range of biological activities, including modulation of various signaling pathways, such as NFkB and ERK, and inhibitory effects on enzymes like Cytochrome P450 3A4. It also demonstrates antiviral activity against SARS-CoV-2, inhibiting virus-induced cytotoxicity in VERO-6 cells at 10 uM. Overall, 8-Cyclopentyl-1,3-dimethylxanthine is a multifaceted molecule with promising therapeutic implications across various biological targets and pathways..
Note: Summary generated by AI. Data source: ChEMBL 
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | 8-Cyclopentyl-1,3-dimethylxanthine (CPT) is a potent antagonist of adenosine A1 receptor. |
| Targets&IC50 | A2 receptor:1440 nM (Ki), A1 receptor:10.9 nM (Ki) |
| Synonyms | CPT |
| Molecular Weight | 248.28 |
| Formula | C12H16N4O2 |
| Cas No. | 35873-49-5 |
| Smiles | Cn1c2[nH]c(nc2c(=O)n(C)c1=O)C1CCCC1 |
| Relative Density. | 1.332 g/cm3 (Predicted) |
| Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 65 mg/mL (261.8 mM), Sonication is recommended.  | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
| ||||||||||||||||||||||||||||||||||||
Calculator
In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, and a total of 10 animals are to be administered, using a formulation of 
10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.Stock Solution Preparation:
Dissolve 2 mg of the compound in 100 μL DMSO to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
Preparation of the In Vivo Formulation:
1) Add 100 μL of the DMSO stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O and mix thoroughly until a homogeneous solution is obtained.
This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
Dose Conversion
You can also refer to dose conversion for different animals. More Dose Conversion
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Keywords
Preview
Related Tags: buy 8-Cyclopentyl-1,3-dimethylxanthine | purchase 8-Cyclopentyl-1,3-dimethylxanthine | 8-Cyclopentyl-1,3-dimethylxanthine cost | order 8-Cyclopentyl-1,3-dimethylxanthine | 8-Cyclopentyl-1,3-dimethylxanthine chemical structure | 8-Cyclopentyl-1,3-dimethylxanthine formula | 8-Cyclopentyl-1,3-dimethylxanthine molecular weight
Generate Quote
Catalog No.: Cas No.:
Add
| Size | Quantity | Unit Price | Amount | Operation |
|---|
Generate Quote
- TOP
Feedback
Hello! How can I help you today? 
Copyright © 2015-2026 TargetMol Chemicals Inc. All Rights Reserved.