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IL-10R alpha/IL-10RA Protein, Human, Recombinant (His)
(Synonyms: interleukin 10 receptor, α, interleukin 10 receptor, alpha, IL-10R1, IL10R, HIL-10R, CDW210A, CD210a, CD210) Copy Product InfoSynonyms: interleukin 10 receptor, α, interleukin 10 receptor, alpha, IL-10R1, IL10R, HIL-10R, CDW210A, CD210a, CD210
Catalog No. TMPY-05338 Copy Product Info
Purity: 98.9%
IL-10R alpha/IL-10RA Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 25.8 kDa and the accession number is Q13651.
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 5 µg | $55 | - | In Stock | |
| 10 µg | $86 | - | In Stock | |
| 20 µg | $139 | - | In Stock | |
| 50 µg | $269 | - | In Stock | |
| 100 µg | $451 | - | In Stock | |
| 200 µg | $798 | 7-10 days | 7-10 days | |
| 500 µg | $1,690 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:98.9%
Appearance:Lyophilized powder
Color:White
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Bioactivity | Measured by its ability to inhibit IL-10 dependent proliferation of MC/9 mouse mast cells. Approximately 0.04-0.2 μg/mL of IL-10Rα will inhibit 50% of the biological response induced by 10 ng/mL of recombinant human IL-10. |
| Description | IL-10R alpha/IL-10RA Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 25.8 kDa and the accession number is Q13651. |
| Species | Human |
| Expression System | HEK293 Cells |
| Tag | C-His |
| Accession Number | Q13651 |
| Construction | A DNA sequence encoding the human IL10RA (NP_001549.2) (Met1-Asn235) was expressed with a polyhistidine tag at the C-terminus. Predicted N terminal: His 22 |
| Protein Purity | > 95 % as determined by SDS-PAGE.  |
| Endotoxin | < 1.0 EU/μg of the protein as determined by the LAL method. |
| Formulation | Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization. |
| Reconstitution | Reconstituted with sterile deionized water to 0.25 mg/mL. Reconstitution conditions may vary depending on the lot. |
| Synonyms | interleukin 10 receptor, α, interleukin 10 receptor, alpha, IL-10R1, IL10R, HIL-10R, CDW210A, CD210a, CD210 |
| Research Background | IL10RA (Interleukin 10 Receptor Subunit Alpha, also known as CD210) is a Protein Coding gene. The protein encoded by this gene is a receptor for interleukin 10. Two transcript variants, one protein-coding, and the other, not protein-coding have been found for this gene. CD210 belongs to the type II cytokine receptor family. This protein is structurally related to interferon receptors. It has been shown to mediate the immunosuppressive signal of interleukin 10, and thus inhibits the synthesis of proinflammatory cytokines. Activation of CD210 leads to tyrosine phosphorylation of JAK1 and TYK2 kinases. CD210 is broadly expressed in the spleen, bone marrow, and other tissues. Diseases associated with IL10RA include Inflammatory Bowel Disease 28, Autosomal Recessive, and Inflammatory Bowel Disease 28. |
| Molecular Weight | 25.8 kDa (predicted) |
| Shipping | In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice. |
| Storage | It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
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Related Tags: IL-10R alpha/IL-10RA Protein, Human, Recombinant (His) chemical structure | IL-10R alpha/IL-10RA Protein, Human, Recombinant (His) molecular weight
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