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BDP FL DBCO

🥰Excellent
Catalog No. T14516Cas No. 2093197-94-3

BDP FL DBCO is a cleavable linker molecule critical for antibody-drug conjugate (ADC) synthesis. BDP FL DBCO enables the covalent attachment of cytotoxic drugs to antibodies, ensuring targeted delivery to cells or proteins, and the cleavable nature facilitates controlled drug release, optimizing the pharmacodynamic effectiveness of ADCs in oncology studies.

BDP FL DBCO

BDP FL DBCO

🥰Excellent
Purity: 99.14%
Catalog No. T14516Cas No. 2093197-94-3
BDP FL DBCO is a cleavable linker molecule critical for antibody-drug conjugate (ADC) synthesis. BDP FL DBCO enables the covalent attachment of cytotoxic drugs to antibodies, ensuring targeted delivery to cells or proteins, and the cleavable nature facilitates controlled drug release, optimizing the pharmacodynamic effectiveness of ADCs in oncology studies.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$67-In Stock
5 mg$162-In Stock
10 mg$245-In Stock
25 mg$493-In Stock
50 mg$719-In Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Batch Information

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Purity:99.14%
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Product Introduction

Bioactivity
Description
BDP FL DBCO is a cleavable linker molecule critical for antibody-drug conjugate (ADC) synthesis. BDP FL DBCO enables the covalent attachment of cytotoxic drugs to antibodies, ensuring targeted delivery to cells or proteins, and the cleavable nature facilitates controlled drug release, optimizing the pharmacodynamic effectiveness of ADCs in oncology studies.
In vitro
The BDP FL DBCO molecule contains a DBCO (dibenzocyclooctyne) group, which can undergo copper-free click chemistry reactions with azides. Its excitation wavelength (λex) and emission wavelength (λem) are 503 nm and 512 nm, respectively [1].
Chemical Properties
Molecular Weight550.41
FormulaC32H29BF2N4O2
Cas No.2093197-94-3
SmilesO=C(NCCC(N1C2=C(C=CC=C2)C#CC3=C(C=CC=C3)C1)=O)CCC4=CC=C5C=C6C(C)=CC(C)=[N]6B(N54)(F)F
Relative Density.1.31g/cm3
ColorOrange
AppearanceSolid
Storage & Solubility Information
Storagekeep away from direct sunlight,store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 100 mg/mL (181.68 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.8168 mL9.0841 mL18.1683 mL90.8414 mL
5 mM0.3634 mL1.8168 mL3.6337 mL18.1683 mL
10 mM0.1817 mL0.9084 mL1.8168 mL9.0841 mL
20 mM0.0908 mL0.4542 mL0.9084 mL4.5421 mL
50 mM0.0363 mL0.1817 mL0.3634 mL1.8168 mL
100 mM0.0182 mL0.0908 mL0.1817 mL0.9084 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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2 Enter the in vivo formulation:
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Keywords

BDP FL DBCO
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