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Anti-Phospho-EIF2S1 (Ser49) Polyclonal Antibody (Synonyms: Phospho-EIF2S1 (S49), p-EIF2S1 (Ser49), p-EIF2S1 (S...)

Catalog No. TMAC-01264 Copy Product Info
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Anti-Phospho-EIF2S1 (Ser49) Polyclonal Antibody is a Rabbit antibody targeting Phospho-EIF2S1 (Ser49). Anti-Phospho-EIF2S1 (Ser49) Polyclonal Antibody can be used in IF,IHC,WB.

Anti-Phospho-EIF2S1 (Ser49) Polyclonal Antibody

Copy Product Info
🥰Excellent
Catalog No. TMAC-01264
Synonyms Phospho-EIF2S1 (S49), p-EIF2S1 (Ser49), p-EIF2S1 (S49), IF2A_HUMAN, Eukaryotic translation initiation factor 2 subunit 1 alpha 35kDa, EIF2S1 (p-Ser49), EIF2S1 (p-S49), EIF2A, EIF2 alpha, EIF2, EIF 2alpha, EIF 2A, EIF 2 alpha, EIF 2

Anti-Phospho-EIF2S1 (Ser49) Polyclonal Antibody is a Rabbit antibody targeting Phospho-EIF2S1 (Ser49). Anti-Phospho-EIF2S1 (Ser49) Polyclonal Antibody can be used in IF,IHC,WB.

Anti-Phospho-EIF2S1
(Ser49) Polyclonal Antibody
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2167-10 days7-10 days
100 μL$3167-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-Phospho-EIF2S1 (Ser49) Polyclonal Antibody is a Rabbit antibody targeting Phospho-EIF2S1 (Ser49). Anti-Phospho-EIF2S1 (Ser49) Polyclonal Antibody can be used in IF,IHC,WB.
SynonymsPhospho-EIF2S1 (S49), p-EIF2S1 (Ser49), p-EIF2S1 (S49), IF2A_HUMAN, Eukaryotic translation initiation factor 2 subunit 1 alpha 35kDa, EIF2S1 (p-Ser49), EIF2S1 (p-S49), EIF2A, EIF2 alpha, EIF2, EIF 2alpha, EIF 2A, EIF 2 alpha, EIF 2
Ig Type
IgG
Reactivity
Human,Mouse,Rat
Verified Activity
1. Western blot analysis of extracts from Hela cells untreated or treated with starvation using eIF2a (phospho-Ser49) Antibody TMAC-01264.
2. Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using eIF2α (Phospho-Ser49) Antibody TMAC-01264 (left) or the same antibody preincubated with blocking peptide #51511 (right).
3. Immunofluorescence staining of methanol-fixed Hela cells using eIF2a (phospho-Ser49) Antibody TMAC-01264.
4. Immunohistochemical analysis of paraffin-embedded human lung carcinoma tissue, using eIF2α (Phospho-Ser49) Antibody TMAC-01264.
verifiedActivityverifiedActivityverifiedActivityverifiedActivity
Application
Antibody Type
Polyclonal
Host SpeciesRabbit
ConstructionPolyclonal Antibody
PurificationAntibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
AppearanceLiquid
FormulationSupplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Research BackgroundFunctions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. This complex binds to a 40S ribosomal subunit, followed by mRNA binding to form a 43S preinitiation complex. Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF-2 and release of an eIF-2-GDP binary complex. In order for eIF-2 to recycle and catalyze another round of initiation, the GDP bound to eIF-2 must exchange with GTP by way of a reaction catalyzed by eIF-2B.
Related Conjugates and Formulations
Conjucates
Unconjugated
Others Formats
Phospho
Antigen Details
Immunogen
Peptide sequence around phosphorylation site of Serine 49 (L-L-S(p)-E-L) derived from Human eIF2a
Antigen Species
human
Uniprot ID
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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