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Anti-Thyroid peroxidase Antibody (7P893)
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Catalog No. TMAY-02533
Alias TPX, thyroid peroxidase, TDH2A, MSA
Anti-Thyroid peroxidase Antibody (7P893) is a Mouse antibody targeting Thyroid peroxidase. Anti-Thyroid peroxidase Antibody (7P893) can be used in ELISA(Cap),IHC-P.
Anti-Thyroid peroxidase Antibody (7P893)
Anti-Thyroid peroxidase Antibody (7P893)
😃Good
Catalog No. TMAY-02533Alias TPX, thyroid peroxidase, TDH2A, MSA
Anti-Thyroid peroxidase Antibody (7P893) is a Mouse antibody targeting Thyroid peroxidase. Anti-Thyroid peroxidase Antibody (7P893) can be used in ELISA(Cap),IHC-P.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 20 μL | $68 | 7-10 days | |
| 100 μL | $199 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-Thyroid peroxidase Antibody (7P893) is a Mouse antibody targeting Thyroid peroxidase. Anti-Thyroid peroxidase Antibody (7P893) can be used in ELISA(Cap),IHC-P. |
| Alias | TPX, thyroid peroxidase, TDH2A, MSA |
| Ig Type | Monoclonal Mouse IgG1 |
| Clone | 7P893 |
| Reactivity | Human |
| Verified Activity | Immunochemical staining of human TPO in human thyroid gland with mouse monoclonal antibody (1:60, formalin-fixed paraffin embedded sections). |
| Application | ELISA(Cap),IHC-P |
| Recommended Dose | IHC-P: 1:50-1:200; ELISA(Cap): 1:250-1:2000 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human Thyroid peroxidase / TPO (rh Thyroid peroxidase / TPO ; TMPY-02779; P07202-1; Met1-Arg846,257Ser/Ala,725Pro/Thr). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Thyroid peroxidase is a membrane-bound glycoprotein which belongs to the peroxidase family, XPO subfamily. It contains 1 EGF-like domain and 1 Sushi (CCP/SCR) domain. Thyroid Peroxidase represents one of the main autoantigenic targets in autoimmune thyroid disease of humans. It used to be taken as the formerly so-called `microsomal antigen` several years ago. As an integral membrane glycoprotein it is restricted to the apical plasma membrane of the follicular epithelial cells and comprises two identical subunits of approx 100 kDa molecular weight. Thyroid peroxidase is an enzyme expressed abundantly in the thyroid that liberates iodine for addition onto tyrosine residues on thyroglobulin for the production of thyroxine or triiodothyronine, thyroid hormones. Thyroid peroxidase plays a key role in the thyroid hormone biosynthesis by catalysing both the iodination of tyrosyl residues and the coupling of iodotyrosyl residues in thyroglobulin to form precursors of the thyroid hormones T4 and T3. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Human Thyroid peroxidase / TPO Protein (TMPY-02779) |
| Antigen Species | Human |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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