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Anti-CD8 alpha Antibody-APC (4G76)
🥰Excellent
Catalog No. TMAY-03586A
Anti-CD8 alpha Antibody-APC (4G76) is a APC-conjugated Rabbit antibody targeting CD8 alpha. Anti-CD8 alpha Antibody-APC (4G76) can be used in FCM.
Anti-CD8 alpha Antibody-APC (4G76)
Anti-CD8 alpha Antibody-APC (4G76)
🥰Excellent
Catalog No. TMAY-03586A
Anti-CD8 alpha Antibody-APC (4G76) is a APC-conjugated Rabbit antibody targeting CD8 alpha. Anti-CD8 alpha Antibody-APC (4G76) can be used in FCM.
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-CD8 alpha Antibody-APC (4G76) is a APC-conjugated Rabbit antibody targeting CD8 alpha. Anti-CD8 alpha Antibody-APC (4G76) can be used in FCM. |
| Ig Type | Monoclonal Rabbit IgG |
| Clone | 4G76 |
| Reactivity | Ferret |
| Verified Activity | Analysis of Ferret CD8A expression on ferret splenocytes. Ferret splenocytes were stained with APC-conjugated rabbit anti-Ferret CD8A. The histogram were derived from the gated events based on light scattering characteristics of viable cells. |
| Application | FCM |
| Recommended Dose | 5 μl/Test, 0.1 mg/ml |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Ferret CD8a / Lyt2 (rF CD8a / Lyt2; TMPY-02165; ABS50091.1; Met1-Glu186) and conjugated with APC under optimum conditions, the unreacted APC was removed. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | PBS solution containing 0.5% BSA and 0.03%ProClin300 |
| Research Background | T-cell surface glycoprotein CD8 alpha chain, also known as CD8a, is a single-pass type I membrane protein. The CD8 glycoprotein is expressed by thymocytes, mature T cells and natural killer (NK) cells and has been implicated in the recognition of monomorphic determinants on major histocompatibility complex (MHC) Class I antigens, and in signal transduction during the course of T-cell activation. Both human and rodent CD8 antigens are comprised of two distinct polypeptide chains, alpha and beta. The Ig domains of CD8 alpha are involved in controlling the ability of CD8 to be expressed. Mutation of B- and F-strand cysteine residues in CD8 alpha reduced the ability of the protein to fold properly and, therefore, to be expressed. Defects in CD8A are a cause of familial CD8 deficiency. Familial CD8 deficiency is a novel autosomal recessive immunologic defect characterized by absence of CD8+ cells, leading to recurrent bacterial infections. |
| Conjucates | APC |
| Others Formats | PerCP/FITC/PE |
| Antibody Types Available | 4 |
| Immunogen | Recombinant Ferret CD8a / Lyt2 protein (TMPY-02165) |
| Antigen Species | Ferret |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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