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Tags Drug-like Compound Libraries

Compound Libraries for HTS/HCS

High-throughput screening and high-content screening (HTS, HCS) are the current mainstream drug screening methods with the advantages of being microscopic, rapid, sensitive, and accurate, and can screen thousands of samples simultaneously. These techniques rely heavily on a large number of compound libraries designed with high structural diversity. And to cover various research fields, the diversity of potential targets must also be considered. There are about 50 million compounds commercially available in the global market, and we apply rigorous selection criteria to only select compounds with reliable quality and good drug-like diversities. During the design and screening process of our compound libraries, we use a series of methods to ensure the diversity and high specificity of our libraries. These libraries have been extensively validated by our in-house bioassays and by the laboratories of over 200 external partners, covering pharmaceutical, biotechnology, academic fields, and screening centers in the US, Europe, and Japan.

Pre-plated Diversity Sets
Pre-plated Diversity Sets
LF1000
For your convenience, there are Diversity Sets of 5,000, 10,000, 15,000, and 20,000 compounds with no structure overlap.
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TargetMol | Inhibitor Hot
Golden Scaffold Library
Golden Scaffold Library
L5610
Diversity: Selected from 1,600,000 drug-like compounds, xnumcompounds representing 5000 scaffolds selected from a large drug-like chemical source;
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TargetMol | Inhibitor Hot
TargetMol | Citations Cited
Mini Scaffold Library
Mini Scaffold Library
L5600
Diversity: Selected from 1,600,000 drug-like compounds covering rich chemical scaffolds, xnum compounds representing xnum scaffolds;
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TargetMol | Inhibitor Hot
TargetMol | Citations Cited
Representative Compounds Library (Bemis-Murcko Clustering Algorithm)
Representative Compounds Library (Bemis-Murcko Clustering Algorithm)
DD3700
300k diverse selection from ChemDiv 1.6M stock is based on Bemis-Murcko clustering workflow:
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TargetMol | Inhibitor Hot
Scaffold Diversity Curated Library
CB3000
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TargetMol | Inhibitor Hot
MCE-18 Trends in Medicinal Chemistry
MCE-18 Trends in Medicinal Chemistry
DP2180
We introduce the original descriptor MCE-18, which stands for Medicinal Chemistry Evolution, 2018, and this measure can effectively score molecules by novelty in terms of their cumulative sp3 complexity.
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3D-Pharmacophore Based Diversity Library
3D-Pharmacophore Based Diversity Library
DD5400
ChemDiv's 3D-Pharmacophore Based Diversity Library contains 48,835 compounds.
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Beyond the Flatland Library sp3 enriched
Beyond the Flatland Library sp3 enriched
DO1000
ChemDiv's Beyond the Flatland Library contains 93,483 compounds.
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Targeted Diversity Library
Targeted Diversity Library
DP1400
ChemDiv introduces the concept of Targeted Diversity which is intended for the design of high quality libraries of drug-like compounds that have been focused against various biological targets.
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DIVERSet-EXP Library
DIVERSet-EXP Library
CB1100
For hit finding across different targets, against novel targets, or for the discovery of new chemical series against existing targets, ChemBridge offers up to 150,000 DIVERSet Library compounds in economical, pre-plated format. The DIVERSet Libraries are
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DNA-encoded (DEL) Reagents and Building Blocks
DNA-encoded (DEL) Reagents and Building Blocks
LF2800
Life Chemicals offers over 70,000 structurally diverse small-molecule compounds, including mono-functional "decorators" as well as protected bi-functional and tri-functional "core" building blocks, scaffolds, and fragment compounds. The presented compound
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