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beta-Neoendorphin acetate(77739-21-0 free base)

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Catalog No. TP2322LCas No. 78658-39-6

beta-Neoendorphin acetate is an agonist of κ-opioid receptor

beta-Neoendorphin acetate(77739-21-0 free base)

beta-Neoendorphin acetate(77739-21-0 free base)

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Purity: 99.91%
Catalog No. TP2322LCas No. 78658-39-6
beta-Neoendorphin acetate is an agonist of κ-opioid receptor
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$80In StockIn Stock
5 mg$181In StockIn Stock
10 mg$272In StockIn Stock
25 mg$448In StockIn Stock
50 mg$630In StockIn Stock
100 mg$852In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
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Batch Information

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Purity:99.91%
Appearance:Solid
Color:White
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COA HNMR LCMS

Product Introduction

Bioactivity
Description
beta-Neoendorphin acetate is an agonist of κ-opioid receptor
In vitro
β-neoendorphin (β-NEP) accelerated wound repair through activation of mitogen-activated protein kinase (MAPK)/Erk1/2 signaling pathways in human keratinocytes.?Moreover, the wound healing effect of β-NEP is mainly through the acceleration of keratinocyte migration without affecting cell proliferation.?Therefore, our studies reveal that β-NEP plays an important role in the regulation of wound repair and suggest a therapeutic strategy to promote wound healing using β-NEP.
Chemical Properties
Molecular Weight1160.34
FormulaC56H81N13O14
Cas No.78658-39-6
SmilesCC(C[C@H](NC([C@@H](NC(CNC(CNC([C@@H](N)CC1=CC=C(O)C=C1)=O)=O)=O)CC2=CC=CC=C2)=O)C(N[C@H](C(N[C@H](C(N[C@H](C(N3CCC[C@H]3C(O)=O)=O)CC4=CC=C(O)C=C4)=O)CCCCN)=O)CCC/N=C(N)\N)=O)C.CC(O)=O
Relative Density.no data available
SequenceH-Tyr-Gly-Gly-Phe-Leu-Arg-Lys-Tyr-Pro-OH.CH3CO2H
Sequence ShortYGGFLRKYP
Storage & Solubility Information
Storagekeep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 10 mM, Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM0.8618 mL4.3091 mL8.6182 mL43.0908 mL
5 mM0.1724 mL0.8618 mL1.7236 mL8.6182 mL
10 mM0.0862 mL0.4309 mL0.8618 mL4.3091 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

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