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EphB1 Protein, Human, Recombinant (hFc)

Catalog No. TMPJ-00403
Synonyms: EPHT2, EPH Tyrosine Kinase 2, EK6, Tyrosine-Protein Kinase Receptor EPH-2, EPH-Like Kinase 6, EPHB1, Ephrin Type-B Receptor 1, Related Tyrosine Kinase, NET, Neuronally-Expressed EPH, hEK6, ELK

Ephrin Type-B Receptor 1 (EPHB1) is a single-pass type I membrane protein that belongs to the Ephrin-B family of receptor tyrosine kinases that is involved in embryonic nervous and vascular system development. EPHB1/EPHT2 contains two fibronectin type-III domains, one protein kinase domain and one SAM (sterile α motif) domain. EPHB1 could stimulate fibroblast motility on extracellular matrix in a kinase-dependent manner, which also correlated with its association with Grb7, an adaptor molecule implicated in the regulation of cell migration. It binds to ephrin-B1, ephrin-B2 and ephrin-B3. EPHB1 plays an important roles in diverse biological processes including nervous system development, angiogenesis, and neural synapsis formation and maturation and may be involved in cell-cell interactions in the nervous system.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.
EphB1 Protein, Human, Recombinant (hFc)
Pack Size Availability Price/USD Quantity
10 μg 5 days $ 184.00
50 μg 5 days $ 526.00
500 μg 5 days $ 2,800.00
1 mg 5 days $ 4,200.00
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Biological Description
Technical Params
Product Properties
Description Ephrin Type-B Receptor 1 (EPHB1) is a single-pass type I membrane protein that belongs to the Ephrin-B family of receptor tyrosine kinases that is involved in embryonic nervous and vascular system development. EPHB1/EPHT2 contains two fibronectin type-III domains, one protein kinase domain and one SAM (sterile α motif) domain. EPHB1 could stimulate fibroblast motility on extracellular matrix in a kinase-dependent manner, which also correlated with its association with Grb7, an adaptor molecule implicated in the regulation of cell migration. It binds to ephrin-B1, ephrin-B2 and ephrin-B3. EPHB1 plays an important roles in diverse biological processes including nervous system development, angiogenesis, and neural synapsis formation and maturation and may be involved in cell-cell interactions in the nervous system.
Species Human
Expression System Human Cells
Tag C-Fc
Accession Number P54762
Synonyms EPHT2, EPH Tyrosine Kinase 2, EK6, Tyrosine-Protein Kinase Receptor EPH-2, EPH-Like Kinase 6, EPHB1, Ephrin Type-B Receptor 1, Related Tyrosine Kinase, NET, Neuronally-Expressed EPH, hEK6, ELK
Amino Acid Met18-Pro540
Construction Recombinant Human Ephrin Type-B Receptor 1 is produced by our Mammalian expression system and the target gene encoding Met18-Pro540 is expressed with a human IgG1 Fc tag at the C-terminus.
Protein Purity Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
Molecular Weight 85-110 KDa, reducing conditions
Endotoxin Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test.
Formulation Lyophilized from a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, pH 8.0.
Reconstitution Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. 
Stability & Storage

Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.
Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature listed below.
Research Background Ephrin Type-B Receptor 1 (EPHB1) is a single-pass type I membrane protein that belongs to the Ephrin-B family of receptor tyrosine kinases that is involved in embryonic nervous and vascular system development. EPHB1/EPHT2 contains two fibronectin type-III domains, one protein kinase domain and one SAM (sterile α motif) domain. EPHB1 could stimulate fibroblast motility on extracellular matrix in a kinase-dependent manner, which also correlated with its association with Grb7, an adaptor molecule implicated in the regulation of cell migration. It binds to ephrin-B1, ephrin-B2 and ephrin-B3. EPHB1 plays an important roles in diverse biological processes including nervous system development, angiogenesis, and neural synapsis formation and maturation and may be involved in cell-cell interactions in the nervous system.

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Keywords

EphB1 Protein, Human, Recombinant (hFc) EPHT2 EPH Tyrosine Kinase 2 EK-6 EK6 EK 6 Tyrosine-Protein Kinase Receptor EPH-2 EPH-Like Kinase 6 EPHT 2 EPHB 1 EPHB1 Ephrin Type-B Receptor 1 Related Tyrosine Kinase NET EPHT-2 Neuronally-Expressed EPH hEK6 ELK EPHB-1 recombinant recombinant-proteins proteins protein

 

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