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EphB1 Protein, Human, Recombinant (hFc)

(Synonyms: Tyrosine-Protein Kinase Receptor EPH-2, Related Tyrosine Kinase, Neuronally-Expressed EPH, NET, hEK6, EPHT2, Ephrin Type-B Receptor 1, EPH-Like Kinase 6, EPHB1, EPH Tyrosine Kinase 2, ELK, EK6) Copy Product Info

Synonyms: Tyrosine-Protein Kinase Receptor EPH-2, Related Tyrosine Kinase, Neuronally-Expressed EPH, NET, hEK6, EPHT2, Ephrin Type-B Receptor 1, EPH-Like Kinase 6, EPHB1, EPH Tyrosine Kinase 2, ELK, EK6

Catalog No. TMPJ-00403 Copy Product Info
Ephrin Type-B Receptor 1 (EPHB1) is a single-pass type I membrane protein that belongs to the Ephrin-B family of receptor tyrosine kinases that is involved in embryonic nervous and vascular system development. EPHB1/EPHT2 contains two fibronectin type-III domains, one protein kinase domain and one SAM (sterile α motif) domain. EPHB1 could stimulate fibroblast motility on extracellular matrix in a kinase-dependent manner, which also correlated with its association with Grb7, an adaptor molecule implicated in the regulation of cell migration. It binds to ephrin-B1, ephrin-B2 and ephrin-B3. EPHB1 plays an important roles in diverse biological processes including nervous system development, angiogenesis, and neural synapsis formation and maturation and may be involved in cell-cell interactions in the nervous system.
Pack SizePriceUSA StockGlobal StockQuantity
5 μg$11235 days35 days
10 μg$18335 days35 days
20 μg$28835 days35 days
50 μg$52635 days35 days
100 μg$86835 days35 days
200 μg$1,43035 days35 days
500 μg$2,80035 days35 days
1 mg$4,20035 days35 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Bioactivity
Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Description
Ephrin Type-B Receptor 1 (EPHB1) is a single-pass type I membrane protein that belongs to the Ephrin-B family of receptor tyrosine kinases that is involved in embryonic nervous and vascular system development. EPHB1/EPHT2 contains two fibronectin type-III domains, one protein kinase domain and one SAM (sterile α motif) domain. EPHB1 could stimulate fibroblast motility on extracellular matrix in a kinase-dependent manner, which also correlated with its association with Grb7, an adaptor molecule implicated in the regulation of cell migration. It binds to ephrin-B1, ephrin-B2 and ephrin-B3. EPHB1 plays an important roles in diverse biological processes including nervous system development, angiogenesis, and neural synapsis formation and maturation and may be involved in cell-cell interactions in the nervous system.
Species
Human
Expression System
HEK293 Cells
TagC-hFc
Accession NumberP54762
Amino AcidMet18-Pro540
ConstructionMet18-Pro540
Protein Purity
Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
Endotoxin< 0.1 ng/µg (1 EU/µg) as determined by LAL test.
FormulationLyophilized from a solution filtered through a 0.22 μm filter, containing 20 mM Tris-HCl, 150 mM NaCl, pH 8.0.
ReconstitutionReconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Stability & StorageLyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
ShippingIn general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
SynonymsTyrosine-Protein Kinase Receptor EPH-2, Related Tyrosine Kinase, Neuronally-Expressed EPH, NET, hEK6, EPHT2, Ephrin Type-B Receptor 1, EPH-Like Kinase 6, EPHB1, EPH Tyrosine Kinase 2, ELK, EK6
Research Background
Chemical Properties
Molecular Weight85-110 KDa (reducing condition)
Storage & Solubility Information
StorageLyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months

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Keywords

Related Tags: EphB1 Protein, Human, Recombinant (hFc) chemical structure | EphB1 Protein, Human, Recombinant (hFc) molecular weight