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Anti-CD155/PVR Antibody (8H169)
😃Good
Catalog No. TMAY-00279
Alias TAGE4, PVS, poliovirus receptor, Necl-5, NECL5, HVED, CD155
Anti-CD155/PVR Antibody (8H169) is a Rabbit antibody targeting CD155/PVR. Anti-CD155/PVR Antibody (8H169) can be used in WB,ELISA.
Anti-CD155/PVR Antibody (8H169)
Anti-CD155/PVR Antibody (8H169)
😃Good
Catalog No. TMAY-00279Alias TAGE4, PVS, poliovirus receptor, Necl-5, NECL5, HVED, CD155
Anti-CD155/PVR Antibody (8H169) is a Rabbit antibody targeting CD155/PVR. Anti-CD155/PVR Antibody (8H169) can be used in WB,ELISA.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μL | $293 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Antibody Type: Rabbit Monoclonal Application: WB, ELISA Reactivity: Human |
| Alias | TAGE4, PVS, poliovirus receptor, Necl-5, NECL5, HVED, CD155 |
| Ig Type | Rabbit IgG |
| Clone | 8H169 |
| Reactivity | Human |
| Verified Activity | 1. Anti-CD155 rabbit monoclonal antibody at 1:500 dilution. -Lane A: HepG2 Whole Cell lysate. -Lysates/proteins at 30 μg per lane. -Secondary -Goat Anti-Rabbit IgG H&L (Dylight800) at 1/10000 dilution. -Developed using the Odyssey technique. -Performed under reducing conditions. -Predicted band size:45 kDa. -Observed band size:92 kDa. 2. Anti-CD155/PVR rabbit monoclonal antibody at 1:500 dilution. -Lane A: 293T Whole Cell Lysate. -Lane B: CD155/PVR konckout 293T Whole Cell lysate. -Lysates/proteins at 30 μg per lane. -Secondary -Goat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution. -Developed using the ECL technique. -Performed under reducing conditions. -Predicted band size:45 kDa. -Observed band size:70 kDa(Validation Experiment) |
| Application | WB,ELISA |
| Recommended Dose | WB: 1:500-1:2000; ELISA: 1:5000-1:10000 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Human CD155 extracellular domain (rh CD155; TMPY-01386; Met 1-Asn 343; P15151-1). |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | CD155, commonly known as PVR (poliovirus receptor) and Necl-5 (nectin-like molecule-5), is a type I transmembrane single-span glycoprotein, and belongs to the nectins and nectin-like (Necl) subfamily. CD155 was originally identified based on its ability to mediate the cell attachment and entry of poliovirus (PV), an etiologic agent of the central nervous system disease poliomyelitis. The normal cellular function is in the establishment of intercellular adherens junctions between epithelial cells. CD155 may assist in an efficient humoral immune response generated within the intestinal immune system. It has been demonstrated that CD155 can be recognized and bond by DNAM-1 and CD96 which promote the adhesion, migration and NK-cell killing, and thus efficiently prime cell-mediated tumor-specific immunity.Cancer ImmunotherapyCo-inhibitory Immune Checkpoint TargetsImmune CheckpointImmune Checkpoint Detection: ELISA AntibodiesImmune Checkpoint Detection: FCM AntibodiesImmune Checkpoint Detection: ICC AntibodiesImmune Checkpoint Detection: IP AntibodiesImmune Checkpoint Detection: WB AntibodiesImmune Checkpoint ProteinsImmune Checkpoint TargetsImmunotherapyTargeted Therapy |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: Human CD155 protein (TMPY-01386) |
| Antigen Species | Human |
| Biology Area | Cancer Drug Targets |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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