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Anti-Phospho-WRN (Ser1141) Polyclonal Antibody is a Rabbit antibody targeting Phospho-WRN (Ser1141). Anti-Phospho-WRN (Ser1141) Polyclonal Antibody can be used in WB,ELISA.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
50 μL | $218 | 7-10 days | |
100 μL | $316 | 7-10 days |
Description | Anti-Phospho-WRN (Ser1141) Polyclonal Antibody is a Rabbit antibody targeting Phospho-WRN (Ser1141). Anti-Phospho-WRN (Ser1141) Polyclonal Antibody can be used in WB,ELISA. |
Ig Type | IgG |
Reactivity | Human |
Application | |
Recommended Dose | WB: 1:500-2000; ELISA: 1:5000 |
Antibody Type | Polyclonal |
Host Species | Rabbit |
Construction | Polyclonal Antibody |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Appearance | Liquid |
Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Research Background | Werner syndrome RecQ like helicase(WRN) Homo sapiens This gene encodes a member of the RecQ subfamily and the DEAH (Asp-Glu-Ala-His) subfamily of DNA and RNA helicases. DNA helicases are involved in many aspects of DNA metabolism, including transcription, replication, recombination, and repair. This protein contains a nuclear localization signal in the C-terminus and shows a predominant nucleolar localization. It possesses an intrinsic 3' to 5' DNA helicase activity, and is also a 3' to 5' exonuclease. Based on interactions between this protein and Ku70/80 heterodimer in DNA end processing, this protein may be involved in the repair of double strand DNA breaks. Defects in this gene are the cause of Werner syndrome, an autosomal recessive disorder characterized by premature aging. [provided by RefSeq, Jul 2008], |
Conjucates | Unconjugated |
Others Formats | Phospho |
Immunogen | A synthesized phosphopeptide: human Werner Syndrome Helicase around the phosphorylation site of Ser1141. AA range:1107-1156 |
Antigen Species | human |
Uniprot ID |
Molecular Weight | Actual: 162 kDa. |
Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
Transport | Shipping with blue ice. |
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