Epiregulin Protein, Mouse, Recombinant (hFc)

Name: Epiregulin Protein, Mouse, Recombinant (hFc)
Brand: TargetMol
SKU: TMPY-02166
Price: 63 USD
Availability: InStock
Rating: 5 (10 reviews)

(Synonyms: EPR, epiregulin) Copy Product Info

Synonyms: EPR, epiregulin

Catalog No. TMPY-02166 Copy Product Info

Purity: 95.7%

Epiregulin Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 33.8 kDa and the accession number is Q61521.

Pack Size	Price	USA Stock	Global Stock
5 µg	$63	-	In Stock
10 µg	$98	-	In Stock
20 µg	$163	-	In Stock
50 µg	$319	-	In Stock
100 µg	$539	-	In Stock
200 µg	$945	7-10 days	7-10 days
500 µg	$1,990	7-10 days	7-10 days
1 mg	$3,520	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Purity:95.7%

Appearance:Lyophilized powder

Color:White

Resource Download

COA User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	Measured in a cell proliferation assay using Balb/3T3 mouse embryonic fibroblast cells. The ED50 for this effect is typically 0.5-2.5 μg/mL.
Description	Epiregulin Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 33.8 kDa and the accession number is Q61521.
Species	Mouse
Expression System	HEK293 Cells
Tag	N-hFc
Accession Number	Q61521
Construction	A DNA sequence encoding the mature form of mouse EREG (Q61521) (Val 56-Leu 101) was fused with the Fc region of human IgG1 at the N-terminus. Predicted N terminal: Glu
Protein Purity	> 95 % as determined by SDS-PAGE
Endotoxin	< 1.0 EU/μg of the protein as determined by the LAL method.
Formulation	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
Reconstitution	A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
Synonyms	EPR, epiregulin
Research Background	Epiregulin (EREG) is a member of the epidermal growth factor family. Epiregulin (EREG) can function as a ligand of EGFR (epidermal growth factor receptor), as well as a ligand of most members of the ERBB (v-erb-b2 oncogene homolog) family of tyrosine-kinase receptors. Epiregulin (EREG) exhibit bifunctional regulatory properties: it inhibit the growth of several epithelial tumor cells and stimulated the growth of fibroblasts and various other types of cells. Epiregulin (EREG) bound to the EGF receptors of epidermoid carcinoma A431 cells much more weakly than did EGF, but was nevertheless much more potent than EGF as a mitogen for rat primary hepatocytes and Balb/c 3T3 A31 fibroblasts. These findings suggest that epiregulin (EREG) plays important roles in regulating the growth of epithelial cells and fibroblasts by binding to receptors for EGF-related ligands. Epiregulin (EREG) is the broadest specificity EGF-like ligand so far characterized: not only does it stimulate homodimers of both ErbB-1 and ErbB-4, it also activates all possible heterodimeric ErbB complexes.

Chemical Properties

Molecular Weight

33.8 kDa (predicted); 37 kDa (reducing conditions)

Storage & Solubility Information

Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Storage	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.