TEM8/ANTXR1 Protein, Human, Recombinant (His)

Name: TEM8/ANTXR1 Protein, Human, Recombinant (His)
Brand: TargetMol
SKU: TMPY-07113
Rating: 4.5 (1 reviews)

(Synonyms: TEM8, GAPO, FLJ21776, FLJ10601, ATR) Copy Product Info

Synonyms: TEM8, GAPO, FLJ21776, FLJ10601, ATR

Catalog No. TMPY-07113 Copy Product Info

TEM8/ANTXR1 Protein, Human, Recombinant (His) is expressed in HEK293 Cells. The accession number is Q9H6X2-1.

Pack Size	Price	USA Stock	Global Stock
5 µg	$87	7-10 days	7-10 days
10 µg	$142	7-10 days	7-10 days
20 µg	$233	7-10 days	7-10 days
50 µg	$535	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	Activity testing is in progress. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Description	TEM8/ANTXR1 Protein, Human, Recombinant (His) is expressed in HEK293 Cells. The accession number is Q9H6X2-1.
Species	Human
Expression System	HEK293 Cells
Tag	C-His
Accession Number	Q9H6X2-1
Construction	A DNA sequence encoding the Human ANTXR1 (NP_115584.1) (Met1-Ser321) was expressed with a polyhistidine tag at the C-terminus.
Protein Purity	≥ 95% as determined by SDS-PAGE. ≥ 95% as determined by SEC-HPLC.
Endotoxin	< 1.0 EU/μg of the protein as determined by the LAL method.
Formulation	Lyophilized from sterile PBS, 10% Glycerol, pH 7.4. Please contact us for any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Reconstitution	Please refer to the lot-specific COA.
Synonyms	TEM8, GAPO, FLJ21776, FLJ10601, ATR
Research Background	ANTXR1 contains 1 VWFA domain and belongs to the ATR family. ATR (Ataxia telangiectasia and Rad3 related) and ATM (Ataxia telangiectasia mutated) are closely related kinases that are activated by DNA damage. They are serine-threonine protein kinases and belongs to the phosphatidylinositol 3' kinase-like kinase (PIKK) family. Upon recruitment by the DNA damage binding proteins/complexes (ATRIP for ATR; MRN for ATM), ATM/ATR initiate the DNA damage checkpoint by phosphorylating a number of key proteins. ANTXR1 interacts with extracellular matrix proteins and with the actin cytoskeleton. It functions in cell attachment and migration. ANTXR1 also mediates adhesion of cells to type 1 collagen and gelatin, reorganization of the actin cytoskeleton and promotes cell spreading. It plays a role in the angiogenic response of cultured umbilical vein endothelial cells.

Chemical Properties

Molecular Weight

33.85 kDa (predicted); 41.1 kDa (reducing contition, due to glycosylation)

Storage & Solubility Information

Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Storage	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.