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TargetMol | Compound Library

Autophagy Compound Library

Catalog No. L3200

Autophagy is the natural, regulated mechanism of the cell that disassembles unnecessary or dysfunctional components. Targeted damaged cytoplasmic constituents are isolated from the rest of the cell within a double-membraned vesicle known as an autophagosome. The autophagosome eventually fuses with lysosomes and the contents are degraded and recycled. Autophagy, cellular senescence, and apoptosis are three key responses of a cell facing a stress, correlating with each other. It has been reported that defects of autophagy are associated with genomic damage, metabolic stress, and tumorigenesis. The Autophagy Compound library by TargetMol contains 1470 compounds with defined autophagy-inducing or -inhibitory activity, and is a useful tool for studying the roles of pro- and anti-autophagic molecules in cells as well as for use in in-vitro applications.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

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Catalog No. L3200

Autophagy Compound Library

sizeIn stock

  • 1 mg
  • 10 μL x 10 mM (in DMSO)
  • 20 μL x 10 mM (in DMSO)
  • 30 μL x 10 mM (in DMSO)
  • 50 μL x 10 mM (in DMSO)
  • 100 μL x 10 mM (in DMSO)
  • 250 μL x 10 mM (in DMSO)
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Product Description Product Description

  • A unique collection of 1470 compounds with defined autophagy-inducing or -inhibitory activity for research in autophagy, high throughput screening (HTS) and high content screening (HCS) for new drugs;
  • Bioactivity and safety confirmed by pre-clinical research and clinical trials;
  • Targets include Autophagy inducers, Autophagy inhibitors, Proteasome, HIF, HDAC, Aurora Kinase, E3 Ligase, mTOR, etc;
  • Detailed compound information with structure, target, activity, IC50 value, and biological activity description;
  • Structurally diverse, medicinally active, and cell permeable;
  • NMR and HPLC validated to ensure high purity and quality;

Packaging And Storage Packaging And Storage

  • Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
  • Shipped with blue ice
  • This compound library is provided at a concentration of 10 mM in DMSO. A small number of compounds may be provided in different solvents or concentrations due to solubility or stability requirements. Please refer to the specific product information for details.

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Library Customization | TargetMol Library Composition

Autophagy
Apoptosis
PI3K
mTOR
Akt
Antibacterial
Endogenous Metabolite
AMPK
GSK-3
NF-κB
Antibiotic
p38 MAPK
Mitophagy
CDK
Parasite
ROS
HIV Protease
ERK
HDAC
Reactive Oxygen Species
CXCR
DNA-PK
Ferroptosis
S6 Kinase
Raf
DNA/RNA Synthesis
ATM/ATR
VEGFR
Potassium Channel
MEK
PKC
Cytochromes P450
Ras
Adrenergic Receptor
COX
Caspase
Bcr-Abl
Src
PDK
Retinoid Receptor
PPAR
Virus Protease
EGFR
Calcium Channel
SARS-CoV
LRRK2
TNF
JNK
PDGFR
STAT
FLT
c-Kit
Influenza Virus
Bcl-2 Family
PKA
Nrf2
Wnt/beta-catenin
Interleukin
Dehydrogenase
Aurora Kinase
Topoisomerase
CaMK
FGFR
AChR
Antifungal
MMP
Casein Kinase
CFTR
5-HT Receptor
PI4K
Estrogen/progestogen Receptor
HMG-CoA Reductase
JAK
FXR
Microtubule Associated
PARP
FAAH
PDE
TLR
HIF/HIF Prolyl-Hydroxylase
HSV
ROCK
Mitochondrial Metabolism
ATPase
IGF-1R
TRP/TRPV Channel
Dopamine Receptor
TGF-beta/Smad
HSP
IL Receptor
PERK
ATG
Beta Amyloid
c-Myc
Proteasome
PTEN
P-gp
MAPK
Glucocorticoid Receptor
c-Met/HGFR
ALK
MDM-2/p53
Sodium Channel
Estrogen Receptor/ERR
SIK
IκB/IKK
c-RET
Phosphatase
p53
Chk
Nucleoside Antimetabolite/Analog
FAK
Rho
Lipoxygenase
HIF
Epigenetic Reader Domain
Proton pump
Serine/threonin kinase
Antioxidant
Sirtuin
SGK
Adenosine Receptor
DYRK
MELK
GABA Receptor
ROS Kinase
Histamine Receptor
Phospholipase
NO Synthase
Trk receptor
NADPH
Anti-infection
Histone Methyltransferase
MRP
Antifection
Progesterone Receptor
Reverse Transcriptase
Integrin
Glucosidase
Hedgehog/Smoothened
HCV Protease
Cysteine Protease
Opioid Receptor
Cannabinoid Receptor
Glucokinase
Gamma-secretase
DUB
Tyrosine Kinases
glycosidase
Transferase
ADC Cytotoxin
Pim
transporter
DNA Methyltransferase
RIP kinase
Drug Metabolite
Fatty Acid Synthase
Androgen Receptor
MAO
NOD
PD-1/PD-L1
DHFR
RAAS
Tie-2
Serotonin Transporter
NOS
Prostaglandin Receptor
FKBP
c-Fms
PLK
Carbonic Anhydrase
GluR
ribosome
NOD-like Receptor (NLR)
Monoamine Oxidase
Antifolate
P2X Receptor
Survivin
Kinesin
GTPase
GST
Reductase
DNA Alkylator/Crosslinker
Glutathione Peroxidase
Aryl Hydrocarbon Receptor
LDL
Cadherin
Tyrosinase
Dynamin
Amino Acids and Derivatives
Ligands for Target Protein for PROTAC
DPP-4
MNK
Syk
S1P Receptor
HBV
ABC Transporter
Monoamine Transporter
Cholinesterase (ChE)
DNA
p62
CRISPR/Cas9
YAP
BACE
IDO
Lipid
Antiviral
BMI-1
AhR
Adenylate cyclase
UGT
Indoleamine 2,3-Dioxygenase (IDO)
GPCR
Mdm2
Histone Acetyltransferase
REV-ERB
Lysosomal Autophagy
NPC1L1
Myosin
DNA Alkylation
Beta-Secretase
FOXO
RAR/RXR
MyD88
Arrestin
IRE1
Norepinephrine
OXPHOS
MLK
ROR
NMDAR
Angiotensin-converting Enzyme (ACE)
Complement System
IAP
iGluR
E1/E2/E3 Enzyme
CCR
ATP Citrate Lyase
HER
Cell wall
Necroptosis
RANKL/RANK
Annexin A
GRK
Na-K-Cl cotransporter
Molecular Glues
ACK1
Thrombin
LPL Receptor
PYK2
Glutaminase
Ligands for E3 Ligase
Somatostatin
BCRP
Aminopeptidase
ASK
DAPK
p97
Y Box Binding Protein 1
Arginase
Na+/Ca2+ Exchanger
gp120/CD4
Photosensitizer
NAMPT
Vasopressin Receptor
cAMP
Ephrin Receptor
Aromatase
Gap Junction Protein
IRAK
TOPK
Cholecystokinin Receptor
CSF-1R
Smo
Endothelin Receptor
Acyltransferase
Decarboxylase
Chloride channel
Melatonin Receptor
Prolyl Endopeptidase (PREP)
DNA gyrase
Guanylate cyclase
MAGL
STING
GluCls
Pyroptosis
Acetyl-CoA Carboxylase
ATTECs
Apelin receptor
Lipase
Serine Protease
Immunology/Inflammation related
PAFR
Hexokinase
GPCR19
VDA
KRas
Sigma receptor
Imidazoline Receptor
BTK
PGC-1α

Keywords