keep away from moisture
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
PNC-28 acetate, a peptide derived from the mdm-2-binding domain (residues 17–26) of the p53 protein featuring a penetratin sequence for membrane crossing, is utilized in pancreatic cancer research [1] [2].
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Description | PNC-28 acetate, a peptide derived from the mdm-2-binding domain (residues 17–26) of the p53 protein featuring a penetratin sequence for membrane crossing, is utilized in pancreatic cancer research [1] [2]. |
In vitro | PNC-28 (0-0.5 mg/mL) can inhibit the growth of lethal human pancreatic cancer cell lines [2]. |
In vivo | PNC-28, administered subcutaneously (SC) or intraperitoneally (IP) at a dose of 2 mg/mouse for a duration of 14 days, effectively inhibited the in vivo growth of BMRPA1 [1]. At a dosage range of 1-20 mg/mouse given SC over 14 days, PNC-28 also suppressed the growth of BMRPA1 Tuc3 tumors [1]. |
Molecular Weight | 3569.18 |
Formula | C164H255N47O37S.C2H4O2 |
keep away from moisture
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. More
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PNC-28 acetate inhibitor inhibit