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TargetMol | Compound Library

Neuroprotective Compound Library

Catalog No. L2640

Neuroprotection refers to the process of safeguarding the nervous system's functionality by preventing neuronal damage or promoting neuronal repair through various mechanisms and approaches. Research in this field primarily focuses on preventing neuronal apoptosis, reducing inflammatory responses, mitigating oxidative stress, and fostering neural regeneration. Neuroprotection holds significant implications for numerous neurodegenerative diseases (such as Alzheimer's disease, Parkinson's disease, multiple sclerosis) and acute neurological injuries (like stroke and spinal cord injury). Studies have unveiled several critical targets, including antioxidants, neurotrophic factors, calcium ion channels, and others, which show potential in preventing neuronal injury, promoting neural regeneration, and combating neurodegenerative diseases.

TargetMol Neuroprotective Compound Library has compiled 1120 compounds with demonstrated neuroprotective activity and potential neuroprotective capabilities. This library can be utilized for drug development related to neuroprotection and for exploring mechanisms associated with neuroprotective actions.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

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Catalog No. L2640

Neuroprotective Compound Library

sizeIn stock

  • 1 mg
  • 30 μL x 10 mM (in DMSO)
  • 50 μL x 10 mM (in DMSO)
  • 100 μL x 10 mM (in DMSO)
  • 250 μL x 10 mM (in DMSO)
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Product Description Product Description

  • A unique collection of 1120 bioactive small molecules with neuroprotective relevance for high throughput screening (HTS) and high content screening (HCS);
  • Targets include Brain-Derived Neurotrophic Factor (BDNF), Calcium Channels, Sodium Channels, N-methyl-D-aspartate receptors (NMDAR), Transient Receptor Potential Melastatin 4 (TRPM4), among others;
  • More detailed compound information with structure, target, activity, IC50 value, and brief introduction;
  • Structurally diverse, medicinally active, and cell permeable;
  • NMR and HPLC validated to ensure high purity and quality;

Packaging And Storage Packaging And Storage

  • Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
  • Shipped with blue ice
  • This compound library is provided at a concentration of 10 mM in DMSO. A small number of compounds may be provided in different solvents or concentrations due to solubility or stability requirements. Please refer to the specific product information for details.

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Calcium Channel
Sodium Channel
Apoptosis
Wnt/beta-catenin
Potassium Channel
iGluR
NO Synthase
Endogenous Metabolite
Autophagy
GSK-3
GABA Receptor
NMDAR
GluR
NF-κB
AMPK
Reactive Oxygen Species
Antibacterial
COX
AChR
Akt
Parasite
CDK
5-HT Receptor
ERK
Cytochromes P450
NOS
PARP
TNF
Caspase
Antioxidant
Dopamine Receptor
Cholinesterase (ChE)
Beta Amyloid
p38 MAPK
PDE
Interleukin
PI3K
IL Receptor
ROS
Histamine Receptor
Mitophagy
PPAR
TRP/TRPV Channel
Adrenergic Receptor
Prostaglandin Receptor
Bcl-2 Family
Antibiotic
HIF/HIF Prolyl-Hydroxylase
Monoamine Oxidase
Adenosine Receptor
PKC
MAO
Influenza Virus
Ferroptosis
JNK
mTOR
EGFR
Tyrosinase
Virus Protease
PKA
Glucosidase
MMP
DNA/RNA Synthesis
STAT
Anti-infection
HIV Protease
Na+/Ca2+ Exchanger
Phosphatase
HSV
TGF-beta/Smad
MAPK
Nrf2
MEK
S6 Kinase
Microtubule Associated
GPCR
Carbonic Anhydrase
Src
RAAS
Mitochondrial Metabolism
Casein Kinase
HDAC
Ras
Sigma receptor
ATPase
Antifungal
Serotonin Transporter
Serine/threonin kinase
VEGFR
Gamma-secretase
Drug Metabolite
Antifection
Molecular Glues
JAK
Aurora Kinase
Epigenetic Reader Domain
Lipoxygenase
Lipid
P-gp
Porcupine
SARS-CoV
transporter
Phospholipase
NOD
Chloride channel
Estrogen/progestogen Receptor
DYRK
PERK
Estrogen Receptor/ERR
Serine Protease
Glucocorticoid Receptor
E1/E2/E3 Enzyme
LDL
Opioid Receptor
PTEN
Chk
Norepinephrine
CaMK
Beta-Secretase
PGE Synthase
Antiviral
TLR
Trk receptor
Sirtuin
Pyroptosis
Cannabinoid Receptor
MDM-2/p53
FLT
HMG-CoA Reductase
Imidazoline Receptor
S1P Receptor
Proteasome
HCV Protease
Integrin
Dehydrogenase
Arginase
LPL Receptor
BACE
Reductase
Cysteine Protease
Leukotriene Receptor
ROCK
NR4A
Amylase
Aryl Hydrocarbon Receptor
Immunology/Inflammation related
Topoisomerase
Bcr-Abl
P2X Receptor
Monoamine Transporter
Guanylate cyclase
Somatostatin
Xanthine Oxidase
cAMP
IGF-1R
ATP Citrate Lyase
HSP
LRRK2
RSV
IκB/IKK
PDK
HIF
FGFR
ROS Kinase
AhR
p53
FOXO3
PGK1
Thyroid hormone receptor(THR)
Proton pump
Adenylyl Cyclase
DHFR
Piezo Channel
Amino Acids and Derivatives
YAP
c-Met/HGFR
LTR
Arrestin
Histone Demethylase
gp120/CD4
GTPase
Progesterone Receptor
OCT
CaSR
MRP
HBV
Cholecystokinin Receptor
Tyrosine Kinases
ASCT
Cell Cycle Arrest
Nucleoside Antimetabolite/Analog
Liver X Receptor
Glucokinase
NAMPT
Glutaminase
IDO
CSF-1R
Prolyl Endopeptidase (PREP)
Myosin
UGT
Raf
DNA gyrase
HCN Channel
DPP-4
Fatty Acid Synthase
PDGFR
Stearoyl-CoA Desaturase (SCD)
CXCR
OX Receptor
Indoleamine 2,3-Dioxygenase (IDO)
Androgen Receptor
Telomerase
SGLT
OXPHOS
Survivin
GPCR19
Ephrin Receptor
Histone Acetyltransferase
Methionine Adenosyltransferase (MAT)
Hippo pathway
GST
Acetyl-CoA Carboxylase
FKBP
Retinoid Receptor
Kras
c-Fms
ribosome
Adenosine Deaminase
DAPK
NADPH-oxidase
DNA Methyltransferase
TAM Receptor
NOD-like Receptor (NLR)
Glyoxalase
PD-1/PD-L1
Sodium-dependent phosphate transporter

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