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3-(2-phenylethynyl)pyridine

Catalog No. T50090 Copy Product Info
Purity: 99.09%
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3-(2-phenylethynyl)pyridine is a pyridine derivative that is a ligand for a variety of receptors in the human body, including dopamine D2 receptors, sigma-1 receptors, and 5-HT6 receptors. It has been studied for the treatment of various neurological disorders, including schizophrenia, depression and Alzheimer's disease.

3-(2-phenylethynyl)pyridine

Copy Product Info
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Catalog No. T50090

3-(2-phenylethynyl)pyridine is a pyridine derivative that is a ligand for a variety of receptors in the human body, including dopamine D2 receptors, sigma-1 receptors, and 5-HT6 receptors. It has been studied for the treatment of various neurological disorders, including schizophrenia, depression and Alzheimer's disease.

3-(2-phenylethynyl)pyridine
Cas No. 13238-38-5
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Pack SizePriceUSA StockGlobal StockQuantity
1 mg$60In StockIn Stock
5 mg$139In StockIn Stock
10 mg$209In StockIn Stock
25 mg$333In StockIn Stock
50 mg$470In StockIn Stock
100 mg$638In StockIn Stock
200 mg$833In StockIn Stock
1 mL x 10 mM (in DMSO)$111In StockIn Stock
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Batch Information

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Purity:99.09%
Appearance:Viscous
Color:Yellow
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Product Introduction

Bioactivity
Description
3-(2-phenylethynyl)pyridine is a pyridine derivative that is a ligand for a variety of receptors in the human body, including dopamine D2 receptors, sigma-1 receptors, and 5-HT6 receptors. It has been studied for the treatment of various neurological disorders, including schizophrenia, depression and Alzheimer's disease.
Chemical Properties
Molecular Weight179.22
FormulaC13H9N
Cas No.13238-38-5
SmilesC(#CC=1C=CC=NC1)C2=CC=CC=C2
Relative Density.1.123g/cm3
Storage & Solubility Information
StoragePure form: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 50 mg/mL (278.99 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM5.5797 mL27.8987 mL55.7973 mL278.9867 mL
5 mM1.1159 mL5.5797 mL11.1595 mL55.7973 mL
10 mM0.5580 mL2.7899 mL5.5797 mL27.8987 mL
20 mM0.2790 mL1.3949 mL2.7899 mL13.9493 mL
50 mM0.1116 mL0.5580 mL1.1159 mL5.5797 mL
100 mM0.0558 mL0.2790 mL0.5580 mL2.7899 mL
Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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