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TRAP1-IN-1

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Catalog No. T79285Cas No. 3031102-94-7

TRAP1-IN-1 (compound 35) is a selective TRAP1 inhibitor that disrupts TRAP1 tetramer stability, induces degradation of TRAP1 downstream proteins, inhibits OXPHOS, and disrupts mitochondrial membrane potential.

TRAP1-IN-1

TRAP1-IN-1

😃Good
Catalog No. T79285Cas No. 3031102-94-7
TRAP1-IN-1 (compound 35) is a selective TRAP1 inhibitor that disrupts TRAP1 tetramer stability, induces degradation of TRAP1 downstream proteins, inhibits OXPHOS, and disrupts mitochondrial membrane potential.
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
TRAP1-IN-1 (compound 35) is a selective TRAP1 inhibitor that disrupts TRAP1 tetramer stability, induces degradation of TRAP1 downstream proteins, inhibits OXPHOS, and disrupts mitochondrial membrane potential.
Chemical Properties
Molecular Weight866.74
FormulaC45H39F7N2O4P2
Cas No.3031102-94-7
SmilesO=C(C1=CC=C(O)C(=C1)C(=O)N2CC3=CC=C(OCCC[P+](C=4C=CC=CC4)(C=5C=CC=CC5)C=6C=CC=CC6)C=C3C2)N7CC=8C=CC=C(F)C8C7.[F-][P+5]([F-])([F-])([F-])([F-])[F-]
ColorWhite
AppearanceSolid
Storage & Solubility Information
Storagekeep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 160 mg/mL (184.6 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.1537 mL5.7687 mL11.5375 mL57.6874 mL
5 mM0.2307 mL1.1537 mL2.3075 mL11.5375 mL
10 mM0.1154 mL0.5769 mL1.1537 mL5.7687 mL
20 mM0.0577 mL0.2884 mL0.5769 mL2.8844 mL
50 mM0.0231 mL0.1154 mL0.2307 mL1.1537 mL
100 mM0.0115 mL0.0577 mL0.1154 mL0.5769 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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2 Enter the in vivo formulation:
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