CD138 (syndecan-1, Sdc-1) is a member of the syndecan family that comprises heparan sulfate proteoglycans. CD138 is significant for cell-cell and cell-matrix interactions.CD138 plays a crucial role in carcinogenesis and is an attractive target for anticancer treatment with heparanase inhibitors and anti-CD138 antibodies for immunotherapy.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
100 μg | 5 days | $ 581.00 | |
500 μg | 5 days | $ 2,330.00 | |
1 mg | 5 days | $ 3,880.00 |
Description | CD138 (syndecan-1, Sdc-1) is a member of the syndecan family that comprises heparan sulfate proteoglycans. CD138 is significant for cell-cell and cell-matrix interactions.CD138 plays a crucial role in carcinogenesis and is an attractive target for anticancer treatment with heparanase inhibitors and anti-CD138 antibodies for immunotherapy. |
Species | Rabbit |
Expression System | HEK293 |
Tag | C-His |
Accession Number | XP_008252990.1 |
Synonyms | SDC1, SYND1, SDC, CD138, Syndecan 1 |
Construction | Recombinant Rabbit Syndecan-1 Protein is expressed from HEK293 with His tag at the C-Terminus. It contains Leu23-Gly254.[Accession |XP_008252990.1] |
Protein Purity | > 90% as determined by Tris-Bis PAGE; > 90% as determined by HPLC |
Molecular Weight | The protein has a predicted MW of 24.57 kDa. Due to glycosylation, the protein migrates to 45-60 kDa based on Tris-Bis PAGE result. |
Endotoxin | Less than 1EU per μg by the LAL method. |
Formulation | Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water. |
Stability & Storage |
-20 to -80°C for 12 months as supplied from date of receipt. -20 to -80°C for 3-6 months in unopened state after reconstitution. 2-8°C for 2-7 days after reconstitution. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
Shipping |
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise. |
Research Background | CD138 (syndecan-1, Sdc-1) is a member of the syndecan family that comprises heparan sulfate proteoglycans. CD138 is significant for cell-cell and cell-matrix interactions.CD138 plays a crucial role in carcinogenesis and is an attractive target for anticancer treatment with heparanase inhibitors and anti-CD138 antibodies for immunotherapy. |
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Syndecan-1 Protein, Rabbit, Recombinant (His) SDC 1 SYND 1 SDC1 SYND1 SYND-1 SDC CD138 CD-138 CD 138 Syndecan 1 SDC-1 recombinant recombinant-proteins proteins protein