Shopping Cart
  • Remove All
  • TargetMol
    Your shopping cart is currently empty

Anti-NBL1 Antibody-HRP (2R803)

😃Good
Catalog No. TMAY-00392H
Alias NO3, neuroblastoma 1, DAN family BMP antagonist, Dana, DAN, D4H1S1733E

Anti-NBL1 Antibody-HRP (2R803) is a HRP-conjugated Mouse antibody targeting NBL1. Anti-NBL1 Antibody-HRP (2R803) can be used in ELISA.

Anti-NBL1 Antibody-HRP (2R803)

Anti-NBL1 Antibody-HRP (2R803)

😃Good
Catalog No. TMAY-00392HAlias NO3, neuroblastoma 1, DAN family BMP antagonist, Dana, DAN, D4H1S1733E
Anti-NBL1 Antibody-HRP (2R803) is a HRP-conjugated Mouse antibody targeting NBL1. Anti-NBL1 Antibody-HRP (2R803) can be used in ELISA.
Pack SizePriceAvailabilityQuantity
100 μg$293 7-10 days
Bulk & Custom
Add to Cart
Questions
View More
Contact us for more batch information
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Product Introduction

Bioactivity
Description
Anti-NBL1 Antibody-HRP (2R803) is a HRP-conjugated Mouse antibody targeting NBL1. Anti-NBL1 Antibody-HRP (2R803) can be used in ELISA.
AliasNO3, neuroblastoma 1, DAN family BMP antagonist, Dana, DAN, D4H1S1733E
Ig Type
Monoclonal Mouse IgG1
Clone
2R803
Reactivity
Human
Application
ELISA
Recommended Dose
ELISA: 0.1-1 μg/ml
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionThis antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human NBL1 / DAND1 / DAN (rh NBL1 / DAND1 / DAN; TMPY-01039; NP_005371.1; Met1-Asp180). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography and conjugated with horseradish-peroxidase (HRP).
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundThe Dan (Differential screening-selected gene aberrative in neuroblastoma, also known as N03) gene was first identified as the putative rat tumor suppressor gene and encodes a protein structurally related to Cerberus and Gremlin in the vertebrates. It is a founding member of the DAN family of secreted proteins, acts as an inhibitor of cell cycle progression, and is closely involved in retinoic acid-induced neuroblastoma differentiation. There are at least five mammalian protein members in the evolutionarily conserved Dan family including DAN, Gremlin/DRM, Cer1 (Cerberus-related), Dante, and PRDC (protein related to DAN and Cerberus), and share the C-terminal cystine-knot motif. As a secreted glycoprotein, DAN is a member of a class of glycoproteins shown to be secreted inhibitors of the transforming growth factor-beta (TGF-beta) and bone morphogenic protein pathways. It binds to BMPs and preventing their interactions with signaling receptor complexes, and accordingly regulates the processes of embryonic development and tissue differentiation. DAN gene product may have an important role in the regulation of the entry of cells into the S phase. Besides, the DAN gene product possesses an ability to revert phenotypes of transformed rat fibroblasts and represents a candidate tumor suppressor gene for neuroblastoma.
Related Conjugates and Formulations
Conjucates
HRP
Others Formats
Unconjugated
Antibody Types Available
2
Antigen Details
Immunogen
Recombinant Human NBL1 / DAND1 / DAN protein (TMPY-01039)
Antigen Species
Human
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. Keep away from direct sunlight.
TransportShipping with blue ice.

Sci Citations

Calculator

  • Molarity Calculator
  • Dilution Calculator
  • Reconstitution Calculator
  • Molecular Weight Calculator

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

Related Tags: buy Anti-NBL1 Antibody-HRP (2R803) | purchase Anti-NBL1 Antibody-HRP (2R803) | Anti-NBL1 Antibody-HRP (2R803) cost | order Anti-NBL1 Antibody-HRP (2R803)