FLT3 Ligand Protein, Mouse, Recombinant (hFc)

Name: FLT3 Ligand Protein, Mouse, Recombinant (hFc)
Brand: TargetMol
SKU: TMPY-03066
Rating: 4.5 (1 reviews)

(Synonyms: Ly72L, fms related tyrosine kinase 3 ligand, Flt3lg, FLT3L) Copy Product Info

Synonyms: Ly72L, fms related tyrosine kinase 3 ligand, Flt3lg, FLT3L

Catalog No. TMPY-03066 Copy Product Info

FLT3 Ligand Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 45.4 kDa and the accession number is P49772-1.

Pack Size	Price	USA Stock	Global Stock
5 µg	$53	7-10 days	7-10 days
10 µg	$97	7-10 days	7-10 days
20 µg	$170	In Stock	-
50 µg	$298	7-10 days	7-10 days
100 µg	$397	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Purity:94%

Appearance:Lyophilized powder

Color:White

Resource Download

COA User Guide of Recombinant Proteins

Product Information

Bioactivity

Bioactivity	Measured in a cell proliferation assay using BaF3 mouse proB cells transfected with mouse Flt3. The ED50 for this effect is typically 7-30 ng/mL.
Description	FLT3 Ligand Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 45.4 kDa and the accession number is P49772-1.
Species	Mouse
Expression System	HEK293 Cells
Tag	C-hFc
Accession Number	P49772-1
Construction	A DNA sequence encoding the mouse FLT3L (P49772-1) (Met1-Arg188) was expressed, fused with the Fc region of human IgG1 at the C-terminus. Predicted N terminal: Gly 27
Protein Purity	> 90 % as determined by SDS-PAGE
Endotoxin	< 1.0 EU/μg of the protein as determined by the LAL method.
Formulation	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
Reconstitution	A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
Synonyms	Ly72L, fms related tyrosine kinase 3 ligand, Flt3lg, FLT3L
Research Background	FLT3L, also known as flt3 ligand, is a small molecule that acts as a growth factor that increases the number of immune cells by activating the hematopoietic progenitors. In vivo, FLT3L also induces the mobilization of the hematopoietic progenitors and stem cells. This may help the system to kill cancer cells. Dendritic cells (DCs) provide the key link between innate and adaptive immunity by recognizing pathogens and priming pathogen-specific immune responses. FLT3L controls the development of DCs and is particularly important for plasmacytoid DCs and CD8 -positive classical DCs and their CD103 -positive tissue counterparts.

Chemical Properties

Molecular Weight

45.4 kDa (predicted); 56 and 35 kDa (reducing condition, due to glycosylation)

Storage & Solubility Information

Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Storage	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.