Shopping Cart

Your shopping cart is currently empty

Dropropizine

Name: Dropropizine
Brand: TargetMol
SKU: T0452
Price: 29 USD
Availability: InStock
Rating: 5 (10 reviews)

😃Good

Catalog No. T0452Cas No. 17692-31-8

Alias UCB-1967, (±)-Dropropizine

Dropropizine (UCB-1967), a racemic non-opiate antitussive agent, is served as a cough suppressant.

Dropropizine

😃Good

Purity: 99.38%

Catalog No. T0452Alias UCB-1967, (±)-DropropizineCas No. 17692-31-8

Dropropizine (UCB-1967), a racemic non-opiate antitussive agent, is served as a cough suppressant.

Pack Size	Price	USA Warehouse	Global Warehouse	Quantity
1 g	$29	-	In Stock
1 mL x 10 mM (in DMSO)	$29	In Stock	In Stock

Add to Cart

Add to Quotation

In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Questions

Batch Information

Select Batch

Purity:99.38%

Appearance:Solid

Color:White

Resource Download

COA HNMR HPLC LCMS

Product Introduction

Bioactivity

Description	Dropropizine (UCB-1967), a racemic non-opiate antitussive agent, is served as a cough suppressant.
In vitro	Dropropizine was not mutagenic or teratogenic in Chinese hamster V79 and human EUE cells, and lithium carbonate showed a weak and mazindol a moderate genotoxic response, which was reduced in both cases in the presence of microsomal fraction S9.
In vivo	Dropropizine was not mutagenic or teratogenic in Chinese hamster V79 and human EUE cells, and lithium carbonate showed a weak and mazindol a moderate genotoxic response, which was reduced in both cases in the presence of microsomal fraction S9.
Synonyms	UCB-1967, (±)-Dropropizine

Chemical Properties

Molecular Weight	236.31
Formula	C₁₃H₂₀N₂O₂
Cas No.	17692-31-8
Smiles	C(C(CO)O)N1CCN(CC1)C2=CC=CC=C2
Relative Density.	1.168 g/cm3

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

H2O: 9 mg/mL (38.09 mM), Sonication is recommended.

DMSO: 55 mg/mL (232.75 mM), Sonication is recommended.

Ethanol: 44 mg/mL (186.2 mM), Sonication is recommended.

Solution Preparation Table

H2O/Ethanol/DMSO

	1mg	5mg	10mg	50mg
1 mM	4.2317 mL	21.1586 mL	42.3173 mL	211.5865 mL
5 mM	0.8463 mL	4.2317 mL	8.4635 mL	42.3173 mL
10 mM	0.4232 mL	2.1159 mL	4.2317 mL	21.1586 mL
20 mM	0.2116 mL	1.0579 mL	2.1159 mL	10.5793 mL

Ethanol/DMSO

	1mg	5mg	10mg	50mg
50 mM	0.0846 mL	0.4232 mL	0.8463 mL	4.2317 mL
100 mM	0.0423 mL	0.2116 mL	0.4232 mL	2.1159 mL

Calculator

Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc