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Anti-KPNA2 Antibody (9N857) (Synonyms: SRP1-α, SRP1-Alpha, SRP1, RCH1, RAG Cohort Protein 1, KPNA2, Karyop...)

Catalog No. TMAC-02337 Copy Product Info
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Anti-KPNA2 Antibody (9N857) is a Rabbit antibody targeting KPNA2. Anti-KPNA2 Antibody (9N857) can be used in FCM,WB.

Anti-KPNA2 Antibody (9N857)

Copy Product Info
🥰Excellent
Catalog No. TMAC-02337
Synonyms SRP1-α, SRP1-Alpha, SRP1, RCH1, RAG Cohort Protein 1, KPNA2, Karyopherin Subunit α-2, Karyopherin Subunit Alpha-2, Importin Subunit α-2, Importin Subunit Alpha-2

Anti-KPNA2 Antibody (9N857) is a Rabbit antibody targeting KPNA2. Anti-KPNA2 Antibody (9N857) can be used in FCM,WB.

Anti-KPNA2 Antibody
(9N857)
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2977-10 days7-10 days
100 μL$4987-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-KPNA2 Antibody (9N857) is a Rabbit antibody targeting KPNA2. Anti-KPNA2 Antibody (9N857) can be used in FCM,WB.
SynonymsSRP1-α, SRP1-Alpha, SRP1, RCH1, RAG Cohort Protein 1, KPNA2, Karyopherin Subunit α-2, Karyopherin Subunit Alpha-2, Importin Subunit α-2, Importin Subunit Alpha-2
Ig Type
IgG
Clone
9N857
Reactivity
Human,Mouse,Rat
Verified Activity
1. Western blot analysis of KPNA2 on different cell lysates using anti-KPNA2 antibody at 1/1,000 dilution. Postive control: Lane 1: Hela, Lane 2: 293T, Lane 3: HepG2, Lane 4: NIH-3T3, Lane 5: PC-12.
2. Flow cytometric analysis of 293T cells with KPNA2 antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black).
verifiedActivityverifiedActivity
Application
Recommended Dose
WB: 1:500-2000; FCM: 1:50-100
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionRecombinant Antibody
PurificationProA affinity purified
AppearanceLiquid
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Research BackgroundFunctions in nuclear protein import as an adapter protein for nuclear receptor KPNB1. Binds specifically and directly to substrates containing either a simple or bipartite NLS motif. Docking of the importin/substrate complex to the nuclear pore complex (NPC) is mediated by KPNB1 through binding to nucleoporin FxFG repeats and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to importin-beta and the three components separate and importin-alpha and -beta are re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran from importin. The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein
Uniprot ID
Chemical Properties
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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