Shopping Cart
- Remove All
- Your shopping cart is currently empty
Anti-KPNA2 Antibody (9N857) is a Rabbit antibody targeting KPNA2. Anti-KPNA2 Antibody (9N857) can be used in WB,FCM.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
50 μL | $297 | 7-10 days | |
100 μL | $498 | 7-10 days |
Description | Anti-KPNA2 Antibody (9N857) is a Rabbit antibody targeting KPNA2. Anti-KPNA2 Antibody (9N857) can be used in WB,FCM. |
Synonyms | SRP1-α, SRP1-Alpha, SRP1, RCH1, RAG Cohort Protein 1, KPNA2, Karyopherin Subunit α-2, Karyopherin Subunit Alpha-2, Importin Subunit α-2, Importin Subunit Alpha-2 |
Ig Type | IgG |
Reactivity | Human,Mouse,Rat |
Verified Activity | 1. Western blot analysis of KPNA2 on different cell lysates using anti-KPNA2 antibody at 1/1,000 dilution. Postive control: Lane 1: Hela, Lane 2: 293T, Lane 3: HepG2, Lane 4: NIH-3T3, Lane 5: PC-12. 2. Flow cytometric analysis of 293T cells with KPNA2 antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). |
Application | |
Recommended Dose | WB: 1:500-2000; FCM: 1:50-100 |
Antibody Type | Monoclonal |
Host Species | Rabbit |
Construction | Recombinant Antibody |
Purification | ProA affinity purified |
Appearance | Liquid |
Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
Research Background | Functions in nuclear protein import as an adapter protein for nuclear receptor KPNB1. Binds specifically and directly to substrates containing either a simple or bipartite NLS motif. Docking of the importin/substrate complex to the nuclear pore complex (NPC) is mediated by KPNB1 through binding to nucleoporin FxFG repeats and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to importin-beta and the three components separate and importin-alpha and -beta are re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran from importin. The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus. |
Conjucates | Unconjugated |
Immunogen | Recombinant Protein |
Uniprot ID |
Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
Transport | Shipping with blue ice. |
Copyright © 2015-2025 TargetMol Chemicals Inc. All Rights Reserved.