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Apiole

Name: Apiole
Brand: TargetMol
SKU: T20402
Price: 109 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T20402Cas No. 523-80-8

Alias NSC-9070, NSC9070, NSC 9070

Apiole (NSC 9070), a phenylpropane volatile compound isolated from parsley, is a calcium channel inhibitor, a mixed-type inhibitor of the CYP1A subfamily, with antitumor activity, induces apoptosis, and inhibits human colon cancer cells by inducing G0/G1 cell cycle arrest.

Apiole

🥰Excellent

Purity: 99.82%

Catalog No. T20402Alias NSC-9070, NSC9070, NSC 9070Cas No. 523-80-8

Pack Size	Price	Availability	Quantity
1 mg	$109	In Stock
5 mg	$269	In Stock

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Purity:99.82%

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Product Introduction

Bioactivity

Description	Apiole (NSC 9070), a phenylpropane volatile compound isolated from parsley, is a calcium channel inhibitor, a mixed-type inhibitor of the CYP1A subfamily, with antitumor activity, induces apoptosis, and inhibits human colon cancer cells by inducing G0/G1 cell cycle arrest.
Synonyms	NSC-9070, NSC9070, NSC 9070

Chemical Properties

Molecular Weight	222.24
Formula	C₁₂H₁₄O₄
Cas No.	523-80-8
Smiles	O(C=1C=C(C(OC)=C2OCOC12)CC=C)C
Relative Density.	1.0150 g/cm3

Storage & Solubility Information

Storage

keep away from direct sunlight,keep away from moisture | Pure form: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 1 mg/mL (4.5 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	4.4996 mL	22.4982 mL	44.9964 mL	224.9820 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc