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Anti-Caspase-14 Antibody-PE (3J760)
🥰Excellent
Catalog No. TMAY-02113P
Anti-Caspase-14 Antibody-PE (3J760) is a PE-conjugated Rabbit antibody targeting Caspase-14. Anti-Caspase-14 Antibody-PE (3J760) can be used in FCM.
Anti-Caspase-14 Antibody-PE (3J760)
Anti-Caspase-14 Antibody-PE (3J760)
🥰Excellent
Catalog No. TMAY-02113P
Anti-Caspase-14 Antibody-PE (3J760) is a PE-conjugated Rabbit antibody targeting Caspase-14. Anti-Caspase-14 Antibody-PE (3J760) can be used in FCM.
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Product Introduction
Bioactivity
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Chemical Properties
| Description | Anti-Caspase-14 Antibody-PE (3J760) is a PE-conjugated Rabbit antibody targeting Caspase-14. Anti-Caspase-14 Antibody-PE (3J760) can be used in FCM. |
| Ig Type | Monoclonal Rabbit IgG |
| Clone | 3J760 |
| Reactivity | Human |
| Verified Activity | Human CASP14 expression in HeLa cells. The cells were treated according to manufacturer’s manual (BD Pharmingen™ Cat. No. 554714), and stained with PE Rabbit anti-CASP14. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of intact cells. |
| Application | FCM |
| Recommended Dose | 10 μl/Test, 0.1 mg/ml |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Human Caspase-14 / CASP14 (rh Caspase-14 / CASP14; TMPY-01824; NP_036246.1; Ser 2-Gln 242) and conjugated with PE under optimum conditions, the unreacted PE was removed. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | PBS solution containing 0.5% BSA and 0.1% sodium azide |
| Research Background | Caspase 14 is a member of the caspase family. Caspases are a kind of cysteine proteinase consisting of a prodomain plus large and small catalytic subunits, that play a central role in cell apoptosis. Caspase 14 possesses an unusually short prodomain and is highly expressed in embryonic tissues but absent from most of the adult tissues except for the skin, which suggests a role in ontogenesis and skin physiology. Unlike the other short prodomain caspases(caspase-3, caspase-6, and caspase-7), Caspase 14 was not processed by multiple death stimuli including activation of members of the tumor necrosis factor receptor family and expression of proapaptotic members of the bcl-2 family. Caspase 14 has been described to be processed and activated by anti-Fas agonist antibody or TNF-related apoptosis inducing ligand in vivo. The expression and processing of this caspase may take part in keratinocyte terminal differentiation, which is essential for the skin barrier. |
| Conjucates | PE |
| Others Formats | FITC |
| Antibody Types Available | 2 |
| Immunogen | Recombinant Human Caspase-14 / CASP14 protein (TMPY-01824) |
| Antigen Species | Human |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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