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Lipoxin B4 (Synonyms: LXB4)

Name: Lipoxin B4
Brand: TargetMol
SKU: T37460
Rating: 4.5 (1 reviews)

Catalog No. T37460 Copy Product Info

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Lipoxin B4 is a metabolite of arachidonic acid that inhibits leukocyte infiltration and mucus secretion in the nasal mucosa of the upper respiratory tract, exhibiting mucosal protective effects. It is commonly used in studies of allergic inflammation in the upper and lower respiratory tracts.

Lipoxin B4

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Catalog No. T37460

Synonyms LXB4

Cas No. 98049-69-5

Pack Size	Price	USA Stock	Global Stock
25 μg	$1,330	35 days	35 days
50 μg	$2,500	35 days	35 days
100 μg	$4,720	35 days	35 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Batch Information

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Appearance:Liquid

Color:Transparent

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Product Introduction

Bioactivity

Description	Lipoxin B4 is a metabolite of arachidonic acid that inhibits leukocyte infiltration and mucus secretion in the nasal mucosa of the upper respiratory tract, exhibiting mucosal protective effects. It is commonly used in studies of allergic inflammation in the upper and lower respiratory tracts.
Synonyms	LXB4

Chemical Properties

Molecular Weight	352.47
Formula	C₂₀H₃₂O₅
Cas No.	98049-69-5
Smiles	[C@H]([C@H](CCCCC)O)(/C=C/C=C/C=C\C=C\[C@H](CCCC(O)=O)O)O

Storage & Solubility Information

Storage

Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMF: 40 mg/mL (113.48 mM), Sonication is recommended.

Ethanol: 40 mg/mL (113.48 mM), Sonication is recommended.

PBS pH 7.2: 1 mg/mL (2.84 mM), Sonication is recommended.

PBS (pH 7.2): >1 mg/mL (from 13(S)-HODE), Sonication is recommended.

Solution Preparation Table

PBS pH 7.2/DMF/Ethanol

	1mg	5mg	10mg	50mg
1 mM	2.8371 mL	14.1856 mL	28.3712 mL	141.8560 mL

DMF/Ethanol

	1mg	5mg	10mg	50mg
5 mM	0.5674 mL	2.8371 mL	5.6742 mL	28.3712 mL
10 mM	0.2837 mL	1.4186 mL	2.8371 mL	14.1856 mL
20 mM	0.1419 mL	0.7093 mL	1.4186 mL	7.0928 mL
50 mM	0.0567 mL	0.2837 mL	0.5674 mL	2.8371 mL
100 mM	0.0284 mL	0.1419 mL	0.2837 mL	1.4186 mL

Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc