IL-4R Protein, Human, Recombinant

Name: IL-4R Protein, Human, Recombinant
Brand: TargetMol
SKU: TMPS-00079
Rating: 4.5 (1 reviews)

(Synonyms: Interleukin-4 receptor, interleukin 4 receptor, IL-4RA, IL4RA, IL4R, CD124) Copy Product Info

Synonyms: Interleukin-4 receptor, interleukin 4 receptor, IL-4RA, IL4RA, IL4R, CD124

Catalog No. TMPS-00079 Copy Product Info

IL-4R Protein, Human, Recombinant is expressed in HEK293 Cells. The accession number is P24394.

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Pack Size	Price	USA Stock	Global Stock
5 µg	$119	7-10 days	7-10 days
10 µg	$198	7-10 days	7-10 days
20 µg	$368	7-10 days	7-10 days
50 µg	$849	7-10 days	7-10 days
100 µg	$1,430	7-10 days	7-10 days
200 µg	$2,470	7-10 days	7-10 days
500 µg	$4,910	7-10 days	7-10 days
1 mg	$8,590	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Bioactivity

Bioactivity	ED 50 < 70.0 ng/ml, measured in a neutralization assay using TF-1 cells in the presence of 0.5 ng/ml h-IL-4.
Description	IL-4R Protein, Human, Recombinant is expressed in HEK293 Cells. The accession number is P24394.
Species	Human
Expression System	HEK293 Cells
Tag	Tag Free
Accession Number	P24394
Construction	Gly24-His232
Protein Purity	> 95% as determined by SDS-PAGE; > 95% as determined by HPLC
Endotoxin	< 0.2 EU/μg of protein as determined by the LAL method.
Formulation	Lyophilized from a 0.2 μm filtered solution in PBS.
Reconstitution	Reconstitute the lyophilized protein in sterile deionized water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Synonyms	Interleukin-4 receptor, interleukin 4 receptor, IL-4RA, IL4RA, IL4R, CD124
Research Background	Interleukin-4 Receptor, also known as IL-4RA and CD124, is a transmembrane glycoprotein belonging to the class I receptor family. It is highly expressed by activated T-cells. IL-4RA couples with γ chain to form the type I receptor for IL-4. The extracellular domain of IL-4RA binds to IL-4 and antagonizes its activity. IL-4RA plays an important role in Th2 cell differentiation, Ig class switching and alternative macrophage activation. It has also been implicated in allergic inflammation, tumor progression and atherogenesis.

Chemical Properties

Molecular Weight

40~45 kDa (Reducing conditions)

Storage & Solubility Information

Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Storage	Upon receiving, this product remains stable for up to 6 months at lower than -70°C. Upon reconstitution, the product should be stable for up to 1 week at 4°C or up to 3 months at -20°C. For long term storage it is recommended that a carrier protein (example 0.1% BSA) be added. Avoid repeated freeze-thaw cycles.