FCGRT & B2M Heterodimer Protein, Human, Recombinant (His & Avi), Biotinylated

Name: FCGRT & B2M Heterodimer Protein, Human, Recombinant (His & Avi), Biotinylated
Brand: TargetMol
SKU: TMPY-05448
Rating: 4.5 (1 reviews)

(Synonyms: α-chain, FCRN, Fc fragment of IgG, receptor, transporter, α, Fc fragment of IgG, receptor, transporter, alpha, alpha-chain) Copy Product Info

Synonyms: α-chain, FCRN, Fc fragment of IgG, receptor, transporter, α, Fc fragment of IgG, receptor, transporter, alpha, alpha-chain

Catalog No. TMPY-05448 Copy Product Info

FCGRT & B2M Heterodimer Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 45.3 kDa and the accession number is NP_004098.1&NP_004039.1.

Pack Size	Price	USA Stock	Global Stock
5 µg	$123	7-10 days	7-10 days
10 µg	$198	7-10 days	7-10 days
20 µg	$347	7-10 days	7-10 days
50 µg	$678	7-10 days	7-10 days
100 µg	$1,380	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	1. Measured by its ability to bind human IgG1 (Fc) in a functional ELISA. 2.Loaded Biotinylated Human FcRn recombinant protein (His & Avi Tag) on SA Biosensor, can bind IgG1 Fc (IgG1) with an affinity constant of 0.073 μM as determined in a BLI assay. 3.Loaded Biotinylated Human FcRn recombinant protein (His & Avi Tag) on SA Biosensor, can bind IgG4 Fc with an affinity constant of 0.070 μM as determined in a BLI assay. 4. The purity of Human FCGRT & B2M Heterodimer Protein (His & AVI Tag), Biotinylated is more than 95% and the molecular weight of this protein is around 46-56 kDa verified by SEC-MALS.
Description	FCGRT & B2M Heterodimer Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 45.3 kDa and the accession number is NP_004098.1&NP_004039.1.
Species	Human
Expression System	HEK293 Cells
Tag	His, Avi
Accession Number	NP_004098.1&NP_004039.1
Construction	A DNA sequence encoding the extracellular domain (Met1-Ser297) of human FCGRT (NP_004098.1) was fused with a C-terminal polyhistidine tagged AVI tag at the C-terminus, constructed the plasmid 1; A DNA sequence encoding the human B2M (NP_004039.1) (Met1-Met119) constructed the plasmid 2. The two plasmids were co-expressed and the human FCGRT/B2M heterodimer was purified. The purified heterodimer was biotinylated in vivo by the Biotin-Protein ligase (BirA enzyme) which is co-expressed. Predicted N terminal: Ala 24 & Ile 21
Protein Purity	> 95 % as determined by SDS-PAGE. > 90 % as determined by SEC-HPLC
Endotoxin	< 1.0 EU/μg of the protein as determined by the LAL method.
Formulation	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
Reconstitution	A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
Synonyms	α-chain, FCRN, Fc fragment of IgG, receptor, transporter, α, Fc fragment of IgG, receptor, transporter, alpha, alpha-chain

Chemical Properties

Molecular Weight

45.3 kDa (predicted)

Storage & Solubility Information

Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Storage	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

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Keywords

a-chain

Related Tags: FCGRT & B2M Heterodimer Protein, Human, Recombinant (His & Avi), Biotinylated chemical structure | FCGRT & B2M Heterodimer Protein, Human, Recombinant (His & Avi), Biotinylated molecular weight