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1-Methyl-2-pentyl-4(1H)-quinolinone

🥰Excellent
Catalog No. TN1175Cas No. 22048-98-2
Alias 1-methyl-2-pentylquinolin-4-one

1-Methyl-2-pentyl-4(1H)-quinolinone, a low toxic natural product containing a quinoline structure, is a specific inhibitor of Plasmodium falciparum type II NADH dehydrogenase (PfNDH2), significantly inhibits Plasmodium falciparum development in the mosquito stage and blocks malaria transmission.

1-Methyl-2-pentyl-4(1H)-quinolinone

1-Methyl-2-pentyl-4(1H)-quinolinone

🥰Excellent
Catalog No. TN1175Alias 1-methyl-2-pentylquinolin-4-oneCas No. 22048-98-2
1-Methyl-2-pentyl-4(1H)-quinolinone, a low toxic natural product containing a quinoline structure, is a specific inhibitor of Plasmodium falciparum type II NADH dehydrogenase (PfNDH2), significantly inhibits Plasmodium falciparum development in the mosquito stage and blocks malaria transmission.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$78-In Stock
5 mg$189-In Stock
10 mgPreferential-In Stock
25 mgPreferential-In Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
1-Methyl-2-pentyl-4(1H)-quinolinone, a low toxic natural product containing a quinoline structure, is a specific inhibitor of Plasmodium falciparum type II NADH dehydrogenase (PfNDH2), significantly inhibits Plasmodium falciparum development in the mosquito stage and blocks malaria transmission.
Synonyms1-methyl-2-pentylquinolin-4-one
Chemical Properties
Molecular Weight229.32
FormulaC15H19NO
Cas No.22048-98-2
SmilesO=C1C=C(N(C=2C=CC=CC12)C)CCCCC
Relative Density.1.032 g/cm3 (Predicted)
ColorWhite
AppearanceSolid
Storage & Solubility Information
Storagekeep away from direct sunlight,store at low temperature,keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 40 mg/mL (174.43 mM), Sonication is recommended.
In Vivo Formulation
10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (8.72 mM), Sonication is recommended.
Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM4.3607 mL21.8036 mL43.6072 mL218.0359 mL
5 mM0.8721 mL4.3607 mL8.7214 mL43.6072 mL
10 mM0.4361 mL2.1804 mL4.3607 mL21.8036 mL
20 mM0.2180 mL1.0902 mL2.1804 mL10.9018 mL
50 mM0.0872 mL0.4361 mL0.8721 mL4.3607 mL
100 mM0.0436 mL0.2180 mL0.4361 mL2.1804 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

1-Methyl-2-pentyl-4(1H)-quinolinone1Methyl2pentyl4(1H)quinolinone1 Methyl 2 pentyl 4(1H) quinolinone
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