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Anti-CD3 epsilon/CD3e Antibody (9X587) (Synonyms: CD3e molecule, ε (CD3-TCR complex), CD3e molecule, epsilon (C...)

Catalog No. TMAB-00353 Copy Product Info
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Anti-CD3 epsilon/CD3e Antibody (9X587) is a Mouse antibody targeting CD3 epsilon/CD3e. Anti-CD3 epsilon/CD3e Antibody (9X587) can be used in FCM.

Anti-CD3 epsilon/CD3e Antibody (9X587)

Copy Product Info
🥰Excellent
Catalog No. TMAB-00353
Synonyms CD3e molecule, ε (CD3-TCR complex), CD3e molecule, epsilon (CD3-TCR complex), CD3 ε/CD3e

Anti-CD3 epsilon/CD3e Antibody (9X587) is a Mouse antibody targeting CD3 epsilon/CD3e. Anti-CD3 epsilon/CD3e Antibody (9X587) can be used in FCM.

Anti-CD3 epsilon/CD3e Antibody
(9X587)
Pack SizePriceUSA StockGlobal StockQuantity
100 μg$3547-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-CD3 epsilon/CD3e Antibody (9X587) is a Mouse antibody targeting CD3 epsilon/CD3e. Anti-CD3 epsilon/CD3e Antibody (9X587) can be used in FCM.
SynonymsCD3e molecule, ε (CD3-TCR complex), CD3e molecule, epsilon (CD3-TCR complex), CD3 ε/CD3e
Ig Type
Mouse IgG2a, k
Clone
9X587
Reactivity
Human
Verified Activity
scatter diagram showing peripheral blood lymphocytes stained with CD3 The cells were incubated with the antibody (TMAB-00353, 1 µg/Test) for 30 min at room temperature. The secondary antibody used for 40 min at room temperature.Acquisition of >20,000 events was performed.
verifiedActivity
Application
Recommended Dose
FCM: 1ug/Test
Antibody Type
Monoclonal
Host SpeciesMouse
Subcellular LocalizationMembrane; Single-pass type I membrane protein.
ConstructionHybridoma Monoclonal Antibody
PurificationProtein G purified
AppearanceLiquid
Formulation0.01M PBS (pH7.4).
Research BackgroundCD3e molecule, epsilon is also known as CD3E, is a T-cell surface single-pass type I membrane glycoprotein. CD3E contains 1 Ig-like (immunoglobulin-like) domain and 1 ITAM domain. CD3E, together with CD3-gamma, CD3-delta and CD3-zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. CD3E plays an essential role in T-cell development, and defects in CD3E gene cause severe immunodeficiency. CD3E gene has also been linked to a susceptibility to type I diabetes in women. CD3E has been shown to interact with TOP2B, CD3EAP and NCK2.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human CD3
Antigen Species
Human
Gene Name
CD3E
Gene ID
Protein Name
T-cell surface glycoprotein CD3 epsilon chain
Uniprot ID
Biology Area
Regulatory T Cells,CD,cd3,Human Lineage Negative
Function
The CD3 complex mediates signal transduction.
Chemical Properties
Molecular WeightTheoretical: 20 kDa. Actual: 20 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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