Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Phototrexate is a photoswitchable potent inhibitor of human dihydrofolate reductase (DHFR). Phototrexate is a photochromic analog of Methotrexate. Antifolate activity is switched on (cis-Phototrexate) by UVA (375 nm) light; it can be switched off (trans-Phototrexate) by blue or white light and by thermal relaxation in the dark.cis-Phototrexate (IC50 = 6 nM) significantly reduces the viability of HeLa cells compared withtrans-Phototrexate (IC50 = 34 μM).
Pack Size | Availability | Price/USD | Quantity |
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5 mg | 35 days | $ 628.00 |
Description | Phototrexate is a photoswitchable potent inhibitor of human dihydrofolate reductase (DHFR). Phototrexate is a photochromic analog of Methotrexate. Antifolate activity is switched on (cis-Phototrexate) by UVA (375 nm) light; it can be switched off (trans-Phototrexate) by blue or white light and by thermal relaxation in the dark.cis-Phototrexate (IC50 = 6 nM) significantly reduces the viability of HeLa cells compared withtrans-Phototrexate (IC50 = 34 μM). |
Molecular Weight | 437.41 |
Formula | C20H19N7O5 |
CAS No. | 2268033-83-4 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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Phototrexate 2268033-83-4 inhibitor inhibit