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CRYAB Protein, Human, Recombinant (His)

Catalog No. TMPJ-00755
Synonyms: α(B)-Crystallin, Alpha(B)-Crystallin, Heat Shock Protein Beta-5, CRYAB, Renal Carcinoma Antigen NY-REN-27, α-Crystallin B Chain, CRYA2, HspB5, Alpha-Crystallin B Chain, Heat Shock Protein β-5, Rosenthal Fiber Component

α Crystallin B Chain (CRYAB) is a cytoplasmic protein that belongs to the small heat shock protein (HSP20) family. Alpha crystallins are composed of two gene products: alpha-A and alpha-B, for acidic and basic, respectively. Alpha crystallins can be induced by heat shock and are members of the small heat shock protein (sHSP also known as the HSP20) family. Alpha crystallins acts as molecular chaperones and hold them in in large soluble aggregates. CRYAB is expressed widely in many tissues and organs. It may contribute to the transparency and refractive index of the lens. The deficiency of CRYAB is the cause of myopathy myofibrillar type 2 (MFM2) and cataract posterior polar type 2 (CTPP2).

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.
CRYAB Protein, Human, Recombinant (His)
Pack Size Availability Price/USD Quantity
10 μg 5 days $ 129.00
50 μg 5 days $ 390.00
500 μg 5 days $ 1,900.00
1 mg 5 days $ 2,730.00
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Biological Description
Technical Params
Product Properties
Description α Crystallin B Chain (CRYAB) is a cytoplasmic protein that belongs to the small heat shock protein (HSP20) family. Alpha crystallins are composed of two gene products: alpha-A and alpha-B, for acidic and basic, respectively. Alpha crystallins can be induced by heat shock and are members of the small heat shock protein (sHSP also known as the HSP20) family. Alpha crystallins acts as molecular chaperones and hold them in in large soluble aggregates. CRYAB is expressed widely in many tissues and organs. It may contribute to the transparency and refractive index of the lens. The deficiency of CRYAB is the cause of myopathy myofibrillar type 2 (MFM2) and cataract posterior polar type 2 (CTPP2).
Species Human
Expression System E. coli
Tag C-6His
Accession Number P02511
Synonyms α(B)-Crystallin, Alpha(B)-Crystallin, Heat Shock Protein Beta-5, CRYAB, Renal Carcinoma Antigen NY-REN-27, α-Crystallin B Chain, CRYA2, HspB5, Alpha-Crystallin B Chain, Heat Shock Protein β-5, Rosenthal Fiber Component
Amino Acid Met1-Lys175
Construction Recombinant Human Crystalline Alpha -B Chain is produced by our E.coli expression system and the target gene encoding Met1-Lys175 is expressed with a 6His tag at the C-terminus.
Protein Purity Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
Molecular Weight 25 KDa, reducing conditions
Endotoxin Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test.
Formulation Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Reconstitution Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. 
Stability & Storage

Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.
Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature listed below.
Research Background α Crystallin B Chain (CRYAB) is a cytoplasmic protein that belongs to the small heat shock protein (HSP20) family. Alpha crystallins are composed of two gene products: alpha-A and alpha-B, for acidic and basic, respectively. Alpha crystallins can be induced by heat shock and are members of the small heat shock protein (sHSP also known as the HSP20) family. Alpha crystallins acts as molecular chaperones and hold them in in large soluble aggregates. CRYAB is expressed widely in many tissues and organs. It may contribute to the transparency and refractive index of the lens. The deficiency of CRYAB is the cause of myopathy myofibrillar type 2 (MFM2) and cataract posterior polar type 2 (CTPP2).

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Keywords

CRYAB Protein, Human, Recombinant (His) α(B)-Crystallin Alpha(B)-Crystallin CRYA 2 Heat Shock Protein Beta-5 CRYA-2 a-Crystallin B Chain CRYAB Renal Carcinoma Antigen NY-REN-27 α-Crystallin B Chain Heat Shock Protein b-5 CRYA2 HspB5 Alpha-Crystallin B Chain Heat Shock Protein β-5 Rosenthal Fiber Component recombinant recombinant-proteins proteins protein

 

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