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Ciclopirox olamine

Name: Ciclopirox olamine
Brand: TargetMol
SKU: T1114
Price: 30 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T1114Cas No. 41621-49-2

Alias Ciclopirox ethanolamine

Ciclopirox olamine is a broad-spectrum antifungal agent with additional antibacterial and anti-inflammatory activities.

Ciclopirox olamine

🥰Excellent

Purity: 99.16%

Catalog No. T1114Alias Ciclopirox ethanolamineCas No. 41621-49-2

Ciclopirox olamine is a broad-spectrum antifungal agent with additional antibacterial and anti-inflammatory activities.

Pack Size	Price	Availability
25 mg	$30	In Stock
50 mg	$43	In Stock
100 mg	$61	In Stock
200 mg	$89	In Stock
500 mg	$148	In Stock
1 mL x 10 mM (in DMSO)	$48	In Stock

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Purity:99.16%

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COA LCMS HNMR

Product Introduction

Bioactivity

Description	Ciclopirox olamine is a broad-spectrum antifungal agent with additional antibacterial and anti-inflammatory activities.
In vivo	Ciclopirox exhibits inhibitory effects on the growth of Candida albicans strain SC5314 (MIC80=1.0-2.0μg/mL) and Aspergillus fumigatus strain B5233 (IC50=4.22 μM).
Cell Research	Sabouraud glucose medium (2%) is used for cell culture growth, and RPMI 2% glucose medium and 2% Sabouraud glucose medium are used for MIC determinations. For cell culture growth curves, 220 mL of 2% Sabouraud glucose medium containing different concentrations of Ciclopirox are inoculated with 105 cells/mL, and the mixture is shaken at 160 rpm and 37 °C for 1-10 hours. Growth is measured photometrically at 630 nm. FeCl3 or 2,2'-bipyridine is added to the medium at different concentrations for inhibition studie(Only for Reference)
Synonyms	Ciclopirox ethanolamine

Chemical Properties

Molecular Weight	268.35
Formula	C₁₄H₂₄N₂O₃
Cas No.	41621-49-2
Smiles	NCCO.Cc1cc(=O)n(O)c(c1)C1CCCCC1
Relative Density.	410 g/L. Temperature:25 °C.
Color	Yellow
Appearance	solid

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

Ethanol: 28 mg/mL (104.34 mM), Sonication is recommended.

H2O: < 1 mg/mL (insoluble or slightly soluble)

DMSO: 3.33 mg/mL (12.42 mM), Sonication is recommended.

Solution Preparation Table

DMSO/Ethanol

	1mg	5mg	10mg	50mg
1 mM	3.7265 mL	18.6324 mL	37.2648 mL	186.3238 mL
5 mM	0.7453 mL	3.7265 mL	7.4530 mL	37.2648 mL
10 mM	0.3726 mL	1.8632 mL	3.7265 mL	18.6324 mL

Ethanol

	1mg	5mg	10mg	50mg
20 mM	0.1863 mL	0.9316 mL	1.8632 mL	9.3162 mL
50 mM	0.0745 mL	0.3726 mL	0.7453 mL	3.7265 mL
100 mM	0.0373 mL	0.1863 mL	0.3726 mL	1.8632 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc