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Anti-Cytokeratin 8 Antibody (7H537)
(Synonyms: KO, K8, K2C8, Cytokeratin8, CYK8, CK-8, CK8, CARD2) Copy Product Info
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Synonyms: KO, K8, K2C8, Cytokeratin8, CYK8, CK-8, CK8, CARD2
Catalog No. TMAY-01276 Copy Product Info
🥰Excellent
Anti-Cytokeratin 8 Antibody (7H537) is a Mouse antibody targeting Cytokeratin 8. Anti-Cytokeratin 8 Antibody (7H537) can be used in ICC/IF,IHC-P.
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 100 μL | $198 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-Cytokeratin 8 Antibody (7H537) is a Mouse antibody targeting Cytokeratin 8. Anti-Cytokeratin 8 Antibody (7H537) can be used in ICC/IF,IHC-P. |
| Synonyms | KO, K8, K2C8, Cytokeratin8, CYK8, CK-8, CK8, CARD2 |
| Ig Type | Mouse IgG1 |
| Clone | 7H537 |
| Reactivity | Human |
| Specificity | Human Cytokeratin 8 |
| Application | |
| Recommended Dose | IHC-P: 1:500-1:5000; ICC-IF: 1:20-1:100 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with a synthetic peptide corresponding to the C-terminus of the Human Cytokeratin 8. The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | KRT8 (Keratin 8) is a Protein Coding gene. 2 alternatively spliced human isoforms have been reported. This gene is a member of the type II keratin family clustered on the long arm of chromosome 12. KRT8 is the major component of the intermediate filament cytoskeleton and is predominantly expressed in simple epithelial tissues. Aberrant expression of KRT8 is associated with multiple tumor progression and metastasis.KRT8 overexpression in renal cancer cell lines promoted cell migration and invasion. In contrast, KRT8 knockdown suppressed ccRCC metastasis both in vitro and in vivo.KRT8 expression may therefore be a biomarker or potential therapeutic target to identify patients with worse survival. Diseases associated with KRT8 include Liver Cirrhosis and Cryptogenic Cirrhosis. |
| Conjucates | Unconjugated |
| Immunogen | A synthetic peptide: C-terminus of the Human Cytokeratin 8 |
| Antigen Species | Human |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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