Lipoprotein lipase

Name: Lipoprotein lipase
Brand: TargetMol
SKU: T73610
Rating: 4.5 (1 reviews)

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Catalog No. T73610Cas No. 9004-02-8

Alias LPL

Lipoprotein lipase (LPL) is an enzyme, mainly involved in lipid metabolism, that hydrolyzes triglycerides in lipoproteins.LPL can be a target for obesity/diabetes-related cardiovascular diseases and has an important role in lowering triglyceride levels and improving cardiovascular.

Lipoprotein lipase

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Catalog No. T73610Alias LPLCas No. 9004-02-8

Pack Size	Price	Availability	Quantity
2 mg	$112	5 days

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Product Introduction

Bioactivity

Description	Lipoprotein lipase (LPL) is an enzyme, mainly involved in lipid metabolism, that hydrolyzes triglycerides in lipoproteins.LPL can be a target for obesity/diabetes-related cardiovascular diseases and has an important role in lowering triglyceride levels and improving cardiovascular.
In vitro	Using mouse/human macrophage cell lines (e.g., RAW264.7, THP-1), lipoprotein lipase (Lipoprotein lipase) was added, and combined with flow cytometry, immunofluorescence, and fluorescence-labeled lipid detection. The Results showed that lipoprotein lipase significantly induced macrophages to polarize towards the M2 phenotype (anti-inflammatory). M2 markers (such as CD206 and CD163) were highly expressed in lipoprotein lipase-treated macrophages, and these cells also demonstrated a significantly enhanced ability to uptake fluorescence-labeled lipids[1].
Synonyms	LPL

Chemical Properties

Cas No.	9004-02-8
Color	Yellow
Appearance	Solid

Storage & Solubility Information

Storage	store at low temperature \| Powder: -20°C for 3 years \| In solvent: -80°C for 1 year \| Shipping with blue ice/Shipping at ambient temperature.
Solubility Information	H2O: 20 mg/mL, Sonication is recommended.

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

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