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Lipoprotein lipase

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Catalog No. T73610Cas No. 9004-02-8
Alias LPL

Lipoprotein lipase (LPL) is an enzyme, mainly involved in lipid metabolism, that hydrolyzes triglycerides in lipoproteins.LPL can be a target for obesity/diabetes-related cardiovascular diseases and has an important role in lowering triglyceride levels and improving cardiovascular.

Lipoprotein lipase

Lipoprotein lipase

😃Good
Catalog No. T73610Alias LPLCas No. 9004-02-8
Lipoprotein lipase (LPL) is an enzyme, mainly involved in lipid metabolism, that hydrolyzes triglycerides in lipoproteins.LPL can be a target for obesity/diabetes-related cardiovascular diseases and has an important role in lowering triglyceride levels and improving cardiovascular.
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2 mg$112 5 days
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Product Introduction

Bioactivity
Description
Lipoprotein lipase (LPL) is an enzyme, mainly involved in lipid metabolism, that hydrolyzes triglycerides in lipoproteins.LPL can be a target for obesity/diabetes-related cardiovascular diseases and has an important role in lowering triglyceride levels and improving cardiovascular.
In vitro
Using mouse/human macrophage cell lines (e.g., RAW264.7, THP-1), lipoprotein lipase (Lipoprotein lipase) was added, and combined with flow cytometry, immunofluorescence, and fluorescence-labeled lipid detection. The Results showed that lipoprotein lipase significantly induced macrophages to polarize towards the M2 phenotype (anti-inflammatory). M2 markers (such as CD206 and CD163) were highly expressed in lipoprotein lipase-treated macrophages, and these cells also demonstrated a significantly enhanced ability to uptake fluorescence-labeled lipids[1].
AliasLPL
Chemical Properties
Cas No.9004-02-8
Storage & Solubility Information
Storagestore at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
H2O: 20 mg/mL, Sonication is recommended.

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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