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Anti-IL-18R alpha Polyclonal Antibody is a Rabbit antibody targeting IL-18R alpha. Anti-IL-18R alpha Polyclonal Antibody can be used in WB.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
50 μL | $222 | 7-10 days | |
100 μL | $373 | 7-10 days | |
200 μL | $528 | 7-10 days |
Description | Anti-IL-18R alpha Polyclonal Antibody is a Rabbit antibody targeting IL-18R alpha. Anti-IL-18R alpha Polyclonal Antibody can be used in WB. |
Synonyms | interleukin 18 receptor 1, IL-1Rrp, IL1RRP, IL18RA, CDw218a, CD218a |
Ig Type | IgG |
Reactivity | Human,Mouse (predicted:Rat,Dog,Pig,Cow) |
Verified Activity | Sample: Lane 1: Mouse Blood cell lysates Lane 2: Mouse Lung tissue lysates Primary: Anti-IL-18R alpha (TMAB-00952) at 1/500 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 60 kDa Observed band size: 70 kDa |
Application | |
Recommended Dose | WB: 1:500-2000 |
Antibody Type | Polyclonal |
Host Species | Rabbit |
Subcellular Localization | Membrane; Single-pass type I membrane protein. |
Tissue Specificity | Expressed in lung, leukocytes, spleen, liver, thymus, prostate, small intestine, colon, placenta, and heart, and is absent from brain, skeletal muscle, pancreas, and kidney. High level of expression in Hodgkin disease cell lines. |
Construction | Polyclonal Antibody |
Purification | Protein A purified |
Appearance | Liquid |
Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
Concentration | 1 mg/mL |
Research Background | The protein encoded by this gene is a cytokine receptor that belongs to the interleukin 1 receptor family. This receptor specifically binds interleukin 18 (IL18), and is essential for IL18 mediated signal transduction. IFN-alpha and IL12 are reported to induce the expression of this receptor in NK and T cells. This gene along with four other members of the interleukin 1 receptor family, including IL1R2, IL1R1, ILRL2 (IL-1Rrp2), and IL1RL1 (T1/ST2), form a gene cluster on chromosome 2q. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2013] |
Immunogen | KLH conjugated synthetic peptide: human IL-18R alpha |
Antigen Species | Human |
Gene Name | IL18R1 |
Gene ID | |
Protein Name | Interleukin-18 receptor 1 |
Uniprot ID | |
Function | Receptor for interleukin 18 (IL-18). Binding to the agonist leads to the activation of NF-kappa-B. |
Molecular Weight | Theoretical: 60 kDa. |
Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
Transport | Shipping with blue ice. |
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