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Anti-DPP4/CD26 Antibody-APC (7W775)
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Catalog No. TMAY-03429A
Alias dipeptidylpeptidase 4
Anti-DPP4/CD26 Antibody-APC (7W775) is a APC-conjugated Rabbit antibody targeting DPP4/CD26. Anti-DPP4/CD26 Antibody-APC (7W775) can be used in FCM.
Anti-DPP4/CD26 Antibody-APC (7W775)
Anti-DPP4/CD26 Antibody-APC (7W775)
😃Good
Catalog No. TMAY-03429AAlias dipeptidylpeptidase 4
Anti-DPP4/CD26 Antibody-APC (7W775) is a APC-conjugated Rabbit antibody targeting DPP4/CD26. Anti-DPP4/CD26 Antibody-APC (7W775) can be used in FCM.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 25 T | $82 | 7-10 days | |
| 100 T | $105 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Antibody Type: Rabbit Monoclonal Application: FCM Reactivity: Mouse |
| Alias | dipeptidylpeptidase 4 |
| Ig Type | Rabbit IgG |
| Clone | 7W775 |
| Reactivity | Mouse |
| Verified Activity | Flow cytometric analysis of Mouse DPP4(CD26) expression on BABL/c splenocytes. Cells were stained with APC-conjugated anti-Mouse DPP4(CD26). The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of intact cells. |
| Application | FCM |
| Recommended Dose | 5 μl/Test, 0.1 mg/ml |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Mouse DPP4 / CD26 (rM DPP4 / CD26; TMPY-00074; NP_034204.1; Ser29-His760) and conjugated with APC under optimum conditions, the unreacted APC was removed. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | PBS solution containing 0.5% BSA and 0.09% sodium azide |
| Research Background | Dipeptidyl peptidase-4 (DPP4) or adenosine deaminase complexing protein 2 (ADCP 2) or T-cell activation antigen CD26 is a serine exopeptidase belonging to the S9B protein family that cleaves X-proline dipeptides from the N-terminus of polypeptides, such as chemokines, neuropeptides, and peptide hormones. The enzyme is a type II transmembrane glycoprotein, expressed on the surface of many cell types. It is also present in serum and other body fluids in a truncated form (sCD26/DPPIV). The soluble CD26 (sCD26) as a tumour marker for the detection of colorectal cancer (CRC) and advanced adenomas. As both a regulatory enzyme and a signalling factor, DPP4 has been evaluated and described in many studies. DPP4 inhibition results in increased blood concentration of the incretin hormones glucagon-like peptide-1 (GLP-1) and gastric inhibitory polypeptide (GIP). This causes an increase in glucose-dependent stimulation, resulting in a lowering of blood glucose levels. Recent studies have shown that DPP4 inhibitors can induce a significant reduction in glycosylated haemoglobin (HbA(1c)) levels, either as monotherapy or as a combination with other antidiabetic agents. Research has also demonstrated that DPP4 inhibitors portray a very low risk of hypoglycaemia development, and are a new pharmacological class of drugs for treating Type 2 diabetes. |
| Conjucates | APC |
| Others Formats | Unconjugated/FITC/PE |
| Antibody Types Available | 4 |
| Immunogen | Recombinant Protein: Mouse DPP4 / CD26 Protein (TMPY-00074) |
| Antigen Species | Mouse |
| Biology Area | Serine Proteases and Regulators |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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