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2-Amino-2-dichlorobenzophenone

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Catalog No. T7918Cas No. 2958-36-3

2-Amino-2-dichlorobenzophenone is an aromatic natural compound that has been used to study the effects of various compounds on cell metabolism, protein synthesis and enzyme activity. It has also been used in the synthesis of drugs, such as antitumor drugs and anti-inflammatory agents.

2-Amino-2-dichlorobenzophenone

2-Amino-2-dichlorobenzophenone

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Purity: 99.42%
Catalog No. T7918Cas No. 2958-36-3
2-Amino-2-dichlorobenzophenone is an aromatic natural compound that has been used to study the effects of various compounds on cell metabolism, protein synthesis and enzyme activity. It has also been used in the synthesis of drugs, such as antitumor drugs and anti-inflammatory agents.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 g$29-In Stock
1 mL x 10 mM (in DMSO)$29In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:99.42%
Appearance:Solid
Color:White
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Product Introduction

2-Amino-2-dichlorobenzophenone AI Summary
2-Amino-2-dichlorobenzophenone exhibits a wide array of bioactivities. It has inhibition potential against RecQ-Like DNA Helicase 1, Influenza NS1 protein function, the malarial parasite plastid, TGF-b, tyrosyl-DNA phosphodiesterase 1 (TDP1), and Vaccinia Orthopoxvirus. It also modulates lipid storage in Drosophila cells, induces DNA re-replication in breast cells, inhibits Vif-A3G interactions, acts as a GLP-1 receptor inverse agonist, and induces synthetic lethality in tumor cells. Additionally, 2-Amino-2-dichlorobenzophenone interacts with the HP1-beta Chromodomain, blocks alpha-synuclein activity, and functions as an antagonist of EPAC2. It also shows potential as a general anesthetic..
Note: Summary generated by AI. Data source: ChEMBL
Bioactivity
Description
2-Amino-2-dichlorobenzophenone is an aromatic natural compound that has been used to study the effects of various compounds on cell metabolism, protein synthesis and enzyme activity. It has also been used in the synthesis of drugs, such as antitumor drugs and anti-inflammatory agents.
Chemical Properties
Molecular Weight266.12
FormulaC13H9Cl2NO
Cas No.2958-36-3
SmilesNC1=C(C=C(Cl)C=C1)C(=O)C1=C(Cl)C=CC=C1
Relative Density.1.373 g/cm3
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 22.5 mg/mL (84.55 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.7577 mL18.7885 mL37.5770 mL187.8852 mL
5 mM0.7515 mL3.7577 mL7.5154 mL37.5770 mL
10 mM0.3758 mL1.8789 mL3.7577 mL18.7885 mL
20 mM0.1879 mL0.9394 mL1.8789 mL9.3943 mL
50 mM0.0752 mL0.3758 mL0.7515 mL3.7577 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
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2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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