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Anti-EMMPRIN/CD147 Antibody (8Q238)
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Catalog No. TMAY-00419
Alias basigin (Ok blood group)
Anti-EMMPRIN/CD147 Antibody (8Q238) is a Mouse antibody targeting EMMPRIN/CD147. Anti-EMMPRIN/CD147 Antibody (8Q238) can be used in ELISA,ELISA(Cap),IHC-P.
Anti-EMMPRIN/CD147 Antibody (8Q238)
Anti-EMMPRIN/CD147 Antibody (8Q238)
😃Good
Catalog No. TMAY-00419Alias basigin (Ok blood group)
Anti-EMMPRIN/CD147 Antibody (8Q238) is a Mouse antibody targeting EMMPRIN/CD147. Anti-EMMPRIN/CD147 Antibody (8Q238) can be used in ELISA,ELISA(Cap),IHC-P.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 20 μL | $69 | 7-10 days | |
| 100 μL | $199 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Antibody Type: Mouse Monoclonal Application: ELISA, ELISA(Cap), IHC-P Reactivity: Human |
| Alias | basigin (Ok blood group) |
| Ig Type | Mouse IgG2a |
| Clone | 8Q238 |
| Reactivity | Human |
| Verified Activity | 1. Immunochemical staining of human CD147 in human stomach with mouse monoclonal antibody (1:60, formalin-fixed paraffin embedded sections). The image showing membrane staining of epithelium cell. 2. Immunochemical staining of human CD147 in human gastric cancer with mouse monoclonal antibody (1:100, formalin-fixed paraffin embedded sections). The image showing membrane staining of epithelium cell. 3. Immunochemical staining of human CD147 in human esophagus with mouse monoclonal antibody (1:100, formalin-fixed paraffin embedded sections). The image showing membrane staining of squamous epithelium cell. |
| Application | ELISA,ELISA(Cap),IHC-P |
| Recommended Dose | ELISA: 1:1000-1:2000; IHC-P: 1:50-1:200; ELISA(Cap): 1:250-1:2000 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human CD147. (rh CD147; NP_940991.1Met 1-His 205). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | CD147/EMMPRIN (Extracellular Matrix Metalloproteinase Inducer), also known as Basigin (BSG), is a transmembrane glycoprotein with different forms resulted from different modes of glycosylation and N-terminal sequence variants. It is a member of the immunoglobulin superfamily with homology to both the immunoglobulin V domain and MHC class II antigen beta-chain. This protein play important roles in variety of events including spermatogenesis, embryo implantation, neural network formation. CD147 induces the production and release of matrix metalloproteinases (MMP) in the surrounding mesenchymal cells and tumor cells, and thereby promotes invasion, metastasis, growth and survival of malignant cells. Furthermore, CD147 also serves as a receptor for extracellular cyclophilinthe and its association with integrins might be important in signal transduction. Recently, CD147 displays increased expression in many cancers, and it has been previously demonstrated to participate in cancer metastasis and progression. Thus, CD147 and its antibody are used as an effective treatment for malignant cancers. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: Human CD147 protein |
| Antigen Species | Human |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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