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GNF-8625 monopyridin-N-piperazine hydrochloride

🥰Excellent
Catalog No. T40034Cas No. 2412055-62-8

GNF-8625 monopyridin-N-piperazine hydrochloride is a tropomyosin receptor kinase (TRK) inhibitor.

GNF-8625 monopyridin-N-piperazine hydrochloride

GNF-8625 monopyridin-N-piperazine hydrochloride

🥰Excellent
Purity: 98.97%
Catalog No. T40034Cas No. 2412055-62-8
GNF-8625 monopyridin-N-piperazine hydrochloride is a tropomyosin receptor kinase (TRK) inhibitor.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$88-In Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products. However, due to objective factors, there is a small probability that the synthesis may not be successful during the R&D process. We appreciate your understanding. If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.
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Batch Information

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Purity:98.97%
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COA FNMR HNMR LCMS

Product Introduction

Bioactivity
Description
GNF-8625 monopyridin-N-piperazine hydrochloride is a tropomyosin receptor kinase (TRK) inhibitor.
Chemical Properties
Molecular Weight479.98
FormulaC25H27ClFN7
Cas No.2412055-62-8
SmilesFC=1C=C([C@@H]2N(C3=NN4C(=CN=C4C=C3)C=5N=C(C=CC5)N6CCNCC6)CCC2)C=CC1.Cl
Relative Density.no data available
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 6.0 mg/mL (12.5 mM), Sonication and heating to 60℃ are recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.0834 mL10.4171 mL20.8342 mL104.1710 mL
5 mM0.4167 mL2.0834 mL4.1668 mL20.8342 mL
10 mM0.2083 mL1.0417 mL2.0834 mL10.4171 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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2 Enter the in vivo formulation:
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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

TrkreceptorTrk receptorTrkGNF-8625 monopyridin-N-piperazine HydrochlorideGNF8625 monopyridinNpiperazine hydrochlorideGNF 8625 monopyridin N piperazine hydrochloride
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